Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1956753..1956898 Replicon chromosome
Accession NZ_CP080353
Organism Klebsiella pneumoniae strain K191663

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1956789..1956891 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1956753..1956898 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K0P45_RS09575 1951883..1953943 + 2061 WP_004151449.1 oligopeptidase B -
K0P45_RS09580 1953947..1954606 - 660 WP_002911407.1 exodeoxyribonuclease X -
K0P45_RS09585 1954685..1954915 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K0P45_RS09590 1955028..1955402 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K0P45_RS09595 1955406..1956275 + 870 WP_009307538.1 copper homeostasis membrane protein CopD -
K0P45_RS09600 1956292..1956630 + 339 WP_009307539.1 YebY family protein -
- 1956753..1956898 - 146 - - Antitoxin
- 1956789..1956891 + 103 - - Toxin
K0P45_RS09605 1957267..1957410 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K0P45_RS09610 1957515..1958483 - 969 WP_004151446.1 VirK/YbjX family protein -
K0P45_RS09615 1958640..1959293 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
K0P45_RS09620 1959290..1959481 - 192 WP_002911395.1 YebW family protein -
K0P45_RS09625 1959579..1959818 - 240 WP_002911393.1 YebV family protein -
K0P45_RS09630 1959934..1961367 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T211747 NZ_CP080353:1956789-1956891 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT211747 NZ_CP080353:c1956898-1956753 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References