Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1968031..1968176 Replicon chromosome
Accession NZ_CP080346
Organism Klebsiella pneumoniae strain K191659

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1968067..1968169 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1968031..1968176 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K0P51_RS09560 1963161..1965221 + 2061 WP_004151449.1 oligopeptidase B -
K0P51_RS09565 1965225..1965884 - 660 WP_002911407.1 exodeoxyribonuclease X -
K0P51_RS09570 1965963..1966193 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K0P51_RS09575 1966306..1966680 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K0P51_RS09580 1966684..1967553 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
K0P51_RS09585 1967570..1967908 + 339 WP_002911404.1 YebY family protein -
- 1968031..1968176 - 146 - - Antitoxin
- 1968067..1968169 + 103 - - Toxin
K0P51_RS09590 1968544..1968687 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K0P51_RS09595 1968792..1969760 - 969 WP_004151446.1 VirK/YbjX family protein -
K0P51_RS09600 1969917..1970570 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
K0P51_RS09605 1970567..1970758 - 192 WP_002911395.1 YebW family protein -
K0P51_RS09610 1970856..1971095 - 240 WP_002911393.1 YebV family protein -
K0P51_RS09615 1971211..1972644 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T211726 NZ_CP080346:1968067-1968169 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT211726 NZ_CP080346:c1968176-1968031 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References