Detailed information of TA system TA021171

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-Phd
• Location: 722927..723486
• Replicon: chromosome
• Accession: NC_006841
• Organism: Vibrio fischeri ES114

Toxin (Protein)

• Gene name: relE
• Uniprot ID: Q5DZS7
• Locus tag: VF_RS16715
• Protein ID: WP_011263487.1
• Coordinates: 722927..723241 (-)
• Length: 105 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: Q5DZS6
• Locus tag: VF_RS16720
• Protein ID: WP_011263488.1
• Coordinates: 723232..723486 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
VF_RS16690	718320..719108	-	789	WP_011263481.1	aminoglycoside phosphotransferase family protein	-
VF_RS16695	719883..720251	+	369	WP_011263482.1	hypothetical protein	-
VF_RS16700	720374..720817	-	444	WP_011263483.1	GNAT family N-acetyltransferase	-
VF_RS16705	720959..721417	-	459	WP_011263484.1	GNAT family N-acetyltransferase	-
VF_RS16710	721572..722771	-	1200	Protein_636	DUF3644 domain-containing protein	-
VF_RS16715	722927..723241	-	315	WP_011263487.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
VF_RS16720	723232..723486	-	255	WP_011263488.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
VF_RS16725	724331..725500	+	1170	WP_011263489.1	hypothetical protein	-
VF_RS16730	725517..726542	+	1026	WP_011263490.1	hypothetical protein	-
VF_RS16735	726708..727160	-	453	WP_011263491.1	GNAT family N-acetyltransferase	-
VF_RS16740	727310..727801	-	492	WP_202904260.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integron	-	-	706054..736001	29947

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-65)

Sequences

Toxin

Protein

• Length: 105 a.a.
• Molecular weight: 12204.10 Da
• Isoelectric Point: 4.5467

>T21171 WP_011263487.1 NC_006841:c723241-722927 [Aliivibrio fischeri ES114]
MAVINWTESALLDLDEIAEYIAINNILAAKALVQSVFHRVERLEDFPLSGRSVPELPHLDYREIVLPPCRIFYKVTNDDI
VYILYVMREERELRQFVLNDRGLQ

Nucleotide

• Length: 315 bp

>T21171 NC_006841:c723241-722927 [Aliivibrio fischeri ES114]
ATGGCTGTAATTAATTGGACTGAATCAGCATTATTAGATTTGGACGAAATTGCAGAATATATCGCTATTAATAATATCTT
AGCGGCTAAGGCGTTAGTTCAATCAGTTTTCCATCGTGTTGAGCGTTTAGAGGATTTTCCATTATCAGGCCGTAGTGTTC
CTGAGCTTCCTCATTTAGATTATCGTGAAATTGTATTGCCACCATGCCGTATTTTTTACAAAGTAACCAACGATGATATT
GTATATATTCTTTATGTCATGAGGGAAGAGCGCGAGTTACGCCAATTTGTTCTCAATGACCGTGGTTTGCAGTAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9562.09 Da
• Isoelectric Point: 7.3180

>AT21171 WP_011263488.1 NC_006841:c723486-723232 [Aliivibrio fischeri ES114]
MKVELVTTLKRQATKILSELHASKEPVLITEHGQPSAYLLDVDDYEFMQKRIAILEGIARGEKAISDNRVVSHEAAKEKM
NKWL

Nucleotide

• Length: 255 bp

>AT21171 NC_006841:c723486-723232 [Aliivibrio fischeri ES114]
ATGAAAGTTGAATTAGTCACTACATTAAAACGTCAAGCAACCAAGATTCTTTCTGAGCTTCATGCTTCAAAAGAACCAGT
GTTAATTACAGAGCACGGTCAACCGTCTGCTTATTTGTTAGATGTTGATGATTACGAGTTTATGCAAAAACGAATTGCTA
TTCTTGAAGGTATTGCTCGCGGTGAAAAAGCAATTTCAGATAATCGTGTAGTTTCTCATGAAGCCGCAAAAGAGAAGATG
AATAAATGGCTGTAA

Structures

Toxin

• AlphaFold DB: Q5DZS7

Antitoxin

• AlphaFold DB: Q5DZS6