Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2008193..2008338 Replicon chromosome
Accession NZ_CP080309
Organism Klebsiella pneumoniae strain KP-426

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2008229..2008331 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2008193..2008338 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KZ481_RS09830 (KZ481_09835) 2003323..2005383 + 2061 WP_004151449.1 oligopeptidase B -
KZ481_RS09835 (KZ481_09840) 2005387..2006046 - 660 WP_002911407.1 exodeoxyribonuclease X -
KZ481_RS09840 (KZ481_09845) 2006125..2006355 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KZ481_RS09845 (KZ481_09850) 2006468..2006842 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KZ481_RS09850 (KZ481_09855) 2006846..2007715 + 870 Protein_1931 copper homeostasis membrane protein CopD -
KZ481_RS09855 (KZ481_09860) 2007732..2008070 + 339 WP_211589099.1 YebY family protein -
- 2008193..2008338 - 146 - - Antitoxin
- 2008229..2008331 + 103 - - Toxin
KZ481_RS09860 (KZ481_09865) 2008706..2008849 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KZ481_RS09865 (KZ481_09870) 2008954..2009922 - 969 WP_004151446.1 VirK/YbjX family protein -
KZ481_RS09870 (KZ481_09875) 2010079..2010732 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
KZ481_RS09875 (KZ481_09880) 2010729..2010920 - 192 WP_002911395.1 YebW family protein -
KZ481_RS09880 (KZ481_09885) 2011018..2011257 - 240 WP_002911393.1 YebV family protein -
KZ481_RS09885 (KZ481_09890) 2011373..2012806 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T211678 NZ_CP080309:2008229-2008331 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT211678 NZ_CP080309:c2008338-2008193 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References