Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1983155..1983666 Replicon chromosome
Accession NC_006513
Organism Aromatoleum aromaticum EbN1

Toxin (Protein)


Gene name relE Uniprot ID Q5P3V9
Locus tag EB_RS09225 Protein ID WP_011237699.1
Coordinates 1983409..1983666 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag EB_RS09220 Protein ID WP_041646111.1
Coordinates 1983155..1983412 (+) Length 86 a.a.

Genomic Context

EB_RS09200EB_RS09205EB_RS09210EB_RS09215EB_RS09220EB_RS09225EB_RS09230EB_RS24675EB_RS09240EB_RS09245EB_RS09235EB_RS09250
Location: 1978868..1979515 (648 bp)
Type: Others
Protein ID: WP_011237693.1
Location: 1979493..1980128 (636 bp)
Type: Others
Protein ID: WP_011237694.1
Location: 1980221..1982305 (2085 bp)
Type: Others
Protein ID: WP_011237696.1
Location: 1982298..1983080 (783 bp)
Type: Others
Protein ID: WP_011237697.1
Location: 1983155..1983412 (258 bp)
Type: Antitoxin
Protein ID: WP_041646111.1
Location: 1983409..1983666 (258 bp)
Type: Toxin
Protein ID: WP_011237699.1
Location: 1983735..1984271 (537 bp)
Type: Others
Protein ID: Protein_1834
Location: 1985300..1985569 (270 bp)
Type: Others
Protein ID: WP_162014362.1
Location: 1985493..1987052 (1560 bp)
Type: Others
Protein ID: WP_041646113.1
Location: 1987075..1987809 (735 bp)
Type: Others
Protein ID: WP_011236010.1
Location: 1984580..1985257 (678 bp)
Type: Others
Protein ID: Protein_1835
Location: 1988016..1988495 (480 bp)
Type: Others
Protein ID: Protein_1839
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EB_RS092001978868..1979515+648WP_011237693.1orotate phosphoribosyltransferase-
EB_RS092051979493..1980128+636WP_011237694.1DUF4124 domain-containing protein-
EB_RS092101980221..1982305+2085WP_011237696.1molybdopterin oxidoreductase family protein-
EB_RS092151982298..1983080+783WP_011237697.1NAD-dependent deacylase-
EB_RS092201983155..1983412+258WP_041646111.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
EB_RS092251983409..1983666+258WP_011237699.1Txe/YoeB family addiction module toxinToxin
EB_RS092301983735..1984271+537Protein_1834transposase-
EB_RS092351984580..1985257-678Protein_1835ISAs1-like element ISAzo29 family transposase-
EB_RS246751985300..1985569+270WP_162014362.1hypothetical protein-
EB_RS092401985493..1987052+1560WP_041646113.1IS21-like element ISAzo4 family transposase-
EB_RS092451987075..1987809+735WP_011236010.1IS21-like element ISAzo4 family helper ATPase IstB-
EB_RS092501988016..1988495-480Protein_1839ISAs1-like element ISAzo29 family transposase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10342.78 Da        Isoelectric Point: 6.7243

>T21149 WP_011237699.1 NC_006513:1983409-1983666 [Aromatoleum aromaticum EbN1]
MRIIFHPQAWDDYLYWQQTDKQILKRVNALIRDIQRDPFDGIGKPEPLKFNLTAYWSRRIDDEHRIVYKVLDDEVIIAQA
RGHYE

Download         Length: 258 bp

>T21149 NC_006513:1983409-1983666 [Aromatoleum aromaticum EbN1]
ATGAGGATTATCTTCCATCCCCAGGCCTGGGACGATTACCTCTACTGGCAGCAGACCGACAAGCAGATCCTCAAGCGGGT
CAATGCGCTGATCCGCGATATCCAACGCGATCCGTTCGACGGCATCGGCAAGCCCGAACCGTTGAAATTCAACCTCACCG
CCTACTGGTCGCGGCGCATCGACGACGAGCACCGCATCGTCTACAAAGTGCTGGACGACGAAGTCATCATTGCGCAGGCG
CGCGGGCACTACGAATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9921.35 Da        Isoelectric Point: 4.8723

>AT21149 WP_041646111.1 NC_006513:1983155-1983412 [Aromatoleum aromaticum EbN1]
MRAITYTDARNNLASELDRVVNDCDVTIITRQKAEATVLMSMREYESLIETAHLLRNPKNAMRLMKAVDDIENRRNLIER
DLIEE

Download         Length: 258 bp

>AT21149 NC_006513:1983155-1983412 [Aromatoleum aromaticum EbN1]
ATGCGAGCCATTACCTATACCGATGCGCGCAACAACCTCGCGTCCGAGCTTGACCGGGTGGTTAACGACTGCGACGTGAC
GATCATCACCCGCCAGAAGGCCGAGGCGACCGTACTGATGTCGATGCGCGAATACGAGTCGTTGATCGAAACCGCTCATC
TACTACGCAATCCGAAGAACGCGATGCGGCTGATGAAGGCCGTCGATGACATCGAGAACCGGCGCAATCTGATCGAGCGG
GACCTGATCGAGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBQ5P3V9

Antitoxin

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Source
ID
Structure
No matching records found

References