Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 1183986..1184569 Replicon chromosome
Accession NC_006513
Organism Aromatoleum aromaticum EbN1

Toxin (Protein)


Gene name vapC Uniprot ID Q5P627
Locus tag EB_RS05600 Protein ID WP_011236958.1
Coordinates 1184186..1184569 (+) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EB_RS05595 Protein ID WP_011236957.1
Coordinates 1183986..1184189 (+) Length 68 a.a.

Genomic Context

EB_RS05565EB_RS05570EB_RS05575EB_RS05580EB_RS05585EB_RS05590EB_RS05595EB_RS05600EB_RS05610EB_RS05615EB_RS05620EB_RS05625EB_RS24130EB_RS05605
Location: 1181424..1181840 (417 bp)
Type: Others
Protein ID: WP_011236951.1
Location: 1181958..1182230 (273 bp)
Type: Others
Protein ID: Protein_1099
Location: 1182291..1182563 (273 bp)
Type: Others
Protein ID: WP_011236953.1
Location: 1182560..1183054 (495 bp)
Type: Others
Protein ID: WP_011236954.1
Location: 1183254..1183568 (315 bp)
Type: Others
Protein ID: WP_011236955.1
Location: 1183571..1183855 (285 bp)
Type: Others
Protein ID: WP_011236956.1
Location: 1183986..1184189 (204 bp)
Type: Antitoxin
Protein ID: WP_011236957.1
Location: 1184186..1184569 (384 bp)
Type: Toxin
Protein ID: WP_011236958.1
Location: 1185132..1185815 (684 bp)
Type: Others
Protein ID: Protein_1107
Location: 1186050..1187618 (1569 bp)
Type: Others
Protein ID: WP_011236587.1
Location: 1187641..1188375 (735 bp)
Type: Others
Protein ID: WP_011235973.1
Location: 1188579..1188992 (414 bp)
Type: Others
Protein ID: Protein_1110
Location: 1180604..1181143 (540 bp)
Type: Others
Protein ID: WP_011236950.1
Location: 1184566..1185006 (441 bp)
Type: Others
Protein ID: WP_157866582.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EB_RS241301180604..1181143-540WP_011236950.1sel1 repeat family protein-
EB_RS055651181424..1181840+417WP_011236951.1pilin-
EB_RS055701181958..1182230+273Protein_1099type II toxin-antitoxin system Phd/YefM family antitoxin-
EB_RS055751182291..1182563+273WP_011236953.1DUF1778 domain-containing protein-
EB_RS055801182560..1183054+495WP_011236954.1GNAT family N-acetyltransferase-
EB_RS055851183254..1183568+315WP_011236955.1type II toxin-antitoxin system Phd/YefM family antitoxin-
EB_RS055901183571..1183855+285WP_011236956.1type II toxin-antitoxin system RelE/ParE family toxin-
EB_RS055951183986..1184189+204WP_011236957.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
EB_RS056001184186..1184569+384WP_011236958.1twitching motility protein PilTToxin
EB_RS056051184566..1185006-441WP_157866582.1GNAT family N-acetyltransferase-
EB_RS056101185132..1185815+684Protein_1107IS21-like element ISAzo17 family transposase-
EB_RS056151186050..1187618+1569WP_011236587.1IS21 family transposase-
EB_RS056201187641..1188375+735WP_011235973.1IS21-like element ISAzo4 family helper ATPase IstB-
EB_RS056251188579..1188992+414Protein_1110IS21 family transposase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-43)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14205.70 Da        Isoelectric Point: 6.2186

>T21145 WP_011236958.1 NC_006513:1184186-1184569 [Aromatoleum aromaticum EbN1]
MKGVLVDTSIWVDHFRQRNDVLVGLLDLDLALTHPMVLVELACRTPPAPRVRTLGDIGLLQQTQQASLREVMDFIEREKL
YGLGCGLVDMVLLASTLITPGAELWTLDKRLAALSERFSVMHQPISR

Download         Length: 384 bp

>T21145 NC_006513:1184186-1184569 [Aromatoleum aromaticum EbN1]
ATGAAAGGCGTCCTGGTCGACACATCGATATGGGTTGACCACTTCCGACAACGCAATGATGTCCTGGTGGGCTTGCTCGA
TCTGGACCTGGCGCTGACGCATCCGATGGTCCTGGTCGAACTTGCGTGCCGAACACCCCCTGCACCGCGAGTTCGGACAC
TCGGCGACATAGGACTGCTTCAACAGACGCAACAGGCGAGTTTGCGCGAGGTGATGGACTTCATTGAACGCGAAAAACTG
TATGGGCTTGGGTGCGGGCTGGTTGACATGGTTTTGTTGGCGTCAACGCTGATCACACCGGGCGCAGAGCTGTGGACGCT
GGACAAGCGCCTGGCCGCGCTGTCGGAACGGTTCAGCGTGATGCACCAACCGATCTCACGCTAG

Antitoxin


Download         Length: 68 a.a.        Molecular weight: 7567.67 Da        Isoelectric Point: 5.0490

>AT21145 WP_011236957.1 NC_006513:1183986-1184189 [Aromatoleum aromaticum EbN1]
MRTTVTIDDDLYEKALEVADPAMDRADLFREAMKTFVRVQAAKRLAALGGTMPEMQDVPRRRGEPSQ

Download         Length: 204 bp

>AT21145 NC_006513:1183986-1184189 [Aromatoleum aromaticum EbN1]
ATGAGAACGACTGTCACGATCGATGATGATCTGTACGAAAAGGCCCTGGAAGTGGCCGATCCGGCTATGGACAGGGCCGA
TCTCTTCCGCGAGGCGATGAAAACTTTCGTTCGGGTACAAGCCGCCAAGCGCCTTGCTGCGTTGGGGGGCACCATGCCGG
AGATGCAGGATGTGCCGCGACGGCGCGGCGAGCCCTCGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBQ5P627

Antitoxin

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Source
ID
Structure
No matching records found

References