Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 910243..910822 Replicon chromosome
Accession NC_006513
Organism Aromatoleum aromaticum EbN1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EB_RS04310 Protein ID WP_197531874.1
Coordinates 910511..910822 (+) Length 104 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID Q5P6U3
Locus tag EB_RS04305 Protein ID WP_011236694.1
Coordinates 910243..910500 (+) Length 86 a.a.

Genomic Context

EB_RS04305EB_RS04310EB_RS04340EB_RS04345EB_RS04285EB_RS04290EB_RS04295EB_RS04300EB_RS04315EB_RS04320EB_RS04325EB_RS04330EB_RS04335
Location: 910243..910500 (258 bp)
Type: Antitoxin
Protein ID: WP_011236694.1
Location: 910511..910822 (312 bp)
Type: Toxin
Protein ID: WP_197531874.1
Location: 914240..914419 (180 bp)
Type: Others
Protein ID: WP_041645754.1
Location: 914431..914850 (420 bp)
Type: Others
Protein ID: WP_041645757.1
Location: 906362..907108 (747 bp)
Type: Others
Protein ID: WP_011236690.1
Location: 907127..907537 (411 bp)
Type: Others
Protein ID: Protein_842
Location: 907580..907918 (339 bp)
Type: Others
Protein ID: WP_041645746.1
Location: 907915..909744 (1830 bp)
Type: Others
Protein ID: WP_011236692.1
Location: 910794..912371 (1578 bp)
Type: Others
Protein ID: WP_011236060.1
Location: 912468..912806 (339 bp)
Type: Others
Protein ID: WP_011236696.1
Location: 912806..913132 (327 bp)
Type: Others
Protein ID: WP_041645449.1
Location: 913431..913751 (321 bp)
Type: Others
Protein ID: WP_041645748.1
Location: 913738..914019 (282 bp)
Type: Others
Protein ID: WP_041645751.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EB_RS04285906362..907108-747WP_011236690.1YdcF family protein-
EB_RS04290907127..907537-411Protein_842cupin domain-containing protein-
EB_RS04295907580..907918-339WP_041645746.1DUF2304 domain-containing protein-
EB_RS04300907915..909744-1830WP_011236692.1glycosyltransferase-
EB_RS04305910243..910500+258WP_011236694.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
EB_RS04310910511..910822+312WP_197531874.1Txe/YoeB family addiction module toxinToxin
EB_RS04315910794..912371-1578WP_011236060.1IS66-like element ISAzo15 family transposase-
EB_RS04320912468..912806-339WP_011236696.1IS66 family insertion sequence element accessory protein TnpB-
EB_RS04325912806..913132-327WP_041645449.1IS66 family insertion sequence hypothetical protein-
EB_RS04330913431..913751-321WP_041645748.1hypothetical protein-
EB_RS04335913738..914019-282WP_041645751.1hypothetical protein-
EB_RS04340914240..914419+180WP_041645754.1type II toxin-antitoxin system HicA family toxin-
EB_RS04345914431..914850+420WP_041645757.1type II toxin-antitoxin system HicB family antitoxin-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 12061.01 Da        Isoelectric Point: 9.1845

>T21141 WP_197531874.1 NC_006513:910511-910822 [Aromatoleum aromaticum EbN1]
MKLAWTLAAWEDYEYWQGQDRKALKRISALIKDCLRHPFEGIGKPEPLKENLSGFWSRRIDDTHRLVYCVDGQALAVIAC
RYHYQCKRPPLPRPLTLAQTLSF

Download         Length: 312 bp

>T21141 NC_006513:910511-910822 [Aromatoleum aromaticum EbN1]
CTGAAACTGGCCTGGACCTTGGCCGCCTGGGAGGATTACGAATACTGGCAAGGCCAGGACCGCAAGGCACTCAAGCGCAT
CAGTGCCTTGATCAAGGACTGCCTGCGCCACCCCTTCGAGGGCATCGGTAAACCTGAGCCCTTGAAAGAAAACCTCTCAG
GCTTCTGGTCGCGCCGCATCGATGACACCCACCGGCTGGTTTACTGTGTCGATGGCCAGGCGCTGGCCGTCATCGCCTGT
CGCTACCACTACCAGTGTAAGCGTCCGCCGCTTCCACGCCCTCTTACGCTTGCGCAGACTCTTTCTTTCTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9551.76 Da        Isoelectric Point: 5.6379

>AT21141 WP_011236694.1 NC_006513:910243-910500 [Aromatoleum aromaticum EbN1]
MRVVNFSEARNNLKNVIDQVIDDADYTVIARRDAPDAVVMSLDTFNGLMETVHLLKSPANAAHLARSIEQYRQGQVKQRD
LPNAD

Download         Length: 258 bp

>AT21141 NC_006513:910243-910500 [Aromatoleum aromaticum EbN1]
ATGCGCGTGGTGAATTTCTCCGAGGCACGAAACAACCTCAAAAACGTGATCGATCAGGTCATCGACGATGCCGACTACAC
GGTCATCGCGCGTCGGGATGCGCCCGATGCGGTGGTGATGTCGCTGGACACCTTCAACGGCCTGATGGAGACGGTCCATC
TGCTCAAGTCGCCGGCCAACGCGGCGCATCTTGCGCGCTCCATCGAGCAGTACCGCCAGGGACAGGTGAAGCAGCGGGAC
CTGCCTAATGCCGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBQ5P6U3

References