21136

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 1733088..1734364 Replicon chromosome
Accession NC_006512
Organism Idiomarina loihiensis L2TR

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag IL_RS13635 Protein ID WP_081423225.1
Coordinates 1733088..1733297 (+) Length 70 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID Q5R0V9
Locus tag IL_RS08275 Protein ID WP_011234857.1
Coordinates 1733297..1734364 (+) Length 356 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IL_RS08255 1728654..1731386 + 2733 WP_011234853.1 DUF2726 domain-containing protein -
IL_RS08260 1731431..1731958 + 528 WP_011234854.1 DUF4433 domain-containing protein -
IL_RS08270 1731924..1733065 + 1142 WP_166649024.1 IS3 family transposase -
IL_RS13635 1733088..1733297 + 210 WP_081423225.1 DUF4433 domain-containing protein Toxin
IL_RS08275 1733297..1734364 + 1068 WP_011234857.1 macro domain-containing protein Antitoxin
IL_RS08280 1734556..1734819 + 264 Protein_1626 type I restriction-modification system subunit M N-terminal domain-containing protein -
IL_RS08285 1734884..1735888 + 1005 WP_011234858.1 SEC-C domain-containing protein -
IL_RS08290 1736062..1736577 + 516 WP_011234859.1 hypothetical protein -
IL_RS08295 1736577..1737380 + 804 WP_011234860.1 DUF3037 domain-containing protein -
IL_RS08300 1737625..1738422 - 798 WP_011234861.1 dioxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1725188..1743299 18111


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(1-69)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 70 a.a.        Molecular weight: 8399.67 Da        Isoelectric Point: 9.8196

>T21136 WP_081423225.1 NC_006512:1733088-1733297 [Idiomarina loihiensis L2TR]
IQRRDFKRDFNDLGKLDRYQAEALIHRHFPITLLKGIVCYDEKVKQFIEQKVGNYGQNIKVINRPDWYF

Download         Length: 210 bp

>T21136 NC_006512:1733088-1733297 [Idiomarina loihiensis L2TR]
ATCCAACGGCGTGACTTTAAACGTGACTTCAATGACTTAGGCAAGCTCGATAGATACCAGGCAGAGGCTTTAATCCACCG
TCACTTCCCTATTACACTTTTAAAAGGTATTGTGTGTTATGACGAAAAAGTAAAACAATTTATCGAACAAAAAGTCGGTA
ACTACGGTCAAAATATAAAAGTCATAAACCGCCCAGATTGGTACTTTTGA

Antitoxin


Download         Length: 356 a.a.        Molecular weight: 40165.03 Da        Isoelectric Point: 6.0669

>AT21136 WP_011234857.1 NC_006512:1733297-1734364 [Idiomarina loihiensis L2TR]
MLNYKTGNLLESEAEALVNTVNTVGVMGKGIALMFKERFPANMEAYSQACKENKVKTGKMFVTHTNELVNPQWIVNFPTK
QHWRAKSKIEWIEEGLKDLRAFIIDNNIRSIAIPPLGAGNGGLDWDNVLPLIQKHLGDMTDIDIQIYQPTQQYQNVSKQS
GVEQLTAARAMIAELIRRYWVLGNECTLLEVQKLAWFLQRAIQQEGKESPLRLTFQPRNYGPYASDLTHLLNRLDGSYLQ
SDKRIPDAKATDVIAFNDNKRETVAAFLQAEATEFQYALDKATEIIEGFESPFGLELLATVDWLMTEGNVNPDADSVIEA
LTYWPAGAKWAQRKLNMFDKKAISIAITALMRKLH

Download         Length: 1068 bp

>AT21136 NC_006512:1733297-1734364 [Idiomarina loihiensis L2TR]
ATGCTCAATTATAAGACAGGCAATTTATTAGAATCTGAAGCTGAAGCCCTTGTTAATACCGTAAATACCGTCGGTGTTAT
GGGTAAAGGGATCGCTTTGATGTTTAAAGAAAGGTTTCCTGCAAATATGGAAGCCTATTCTCAGGCCTGTAAAGAGAATA
AAGTGAAGACAGGCAAAATGTTCGTTACTCACACCAACGAACTGGTCAACCCTCAATGGATCGTGAACTTTCCGACAAAG
CAACATTGGCGTGCCAAATCAAAAATAGAATGGATTGAAGAAGGGTTAAAAGATTTAAGAGCTTTCATTATTGATAATAA
CATTCGCTCAATTGCTATCCCTCCTCTAGGAGCAGGCAATGGTGGCTTAGACTGGGATAACGTTCTTCCCCTGATACAAA
AGCATCTGGGCGATATGACTGACATCGATATTCAAATTTATCAGCCTACGCAGCAGTACCAAAACGTCAGCAAACAATCT
GGAGTTGAGCAACTAACAGCTGCTCGAGCAATGATTGCAGAGCTGATAAGACGTTACTGGGTATTAGGTAATGAATGTAC
CCTACTTGAGGTGCAAAAGCTTGCATGGTTCCTGCAACGAGCCATACAGCAAGAAGGGAAAGAGAGCCCACTTAGACTGA
CCTTTCAGCCCAGAAATTACGGACCCTATGCCAGTGACTTAACGCACTTATTAAATCGATTAGATGGCAGCTATTTACAG
TCGGACAAGCGTATTCCCGACGCAAAAGCGACAGATGTGATTGCCTTTAATGATAATAAGCGGGAAACCGTTGCAGCTTT
CCTACAAGCCGAAGCAACTGAGTTTCAATATGCATTGGACAAAGCGACAGAAATTATTGAAGGGTTCGAATCTCCCTTTG
GACTCGAGCTGCTCGCGACAGTTGACTGGCTGATGACTGAGGGGAACGTAAATCCAGACGCGGATAGTGTAATAGAAGCA
TTAACCTATTGGCCTGCTGGTGCTAAATGGGCGCAGCGCAAACTAAATATGTTTGATAAAAAGGCCATCTCAATTGCTAT
CACCGCATTAATGAGAAAGCTGCACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB Q5R0V9

References