Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1118150..1118421 Replicon chromosome
Accession NZ_CP080235
Organism Escherichia coli O139:H1 strain W13-16

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1118188..1118291 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1118150..1118421 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KZW92_RS05725 1115307..1116746 + 1440 WP_219789629.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
KZW92_RS05730 1116864..1117100 + 237 WP_001295499.1 YebV family protein -
KZW92_RS05735 1117205..1117396 + 192 WP_001296140.1 YebW family protein -
KZW92_RS05740 1117397..1118053 - 657 WP_001520704.1 protein-serine/threonine phosphatase -
- 1118150..1118421 + 272 - - Antitoxin
- 1118188..1118291 - 104 - - Toxin
KZW92_RS05745 1118449..1118790 - 342 WP_000976472.1 YebY family protein -
KZW92_RS05750 1118803..1119675 - 873 WP_000879330.1 copper homeostasis membrane protein CopD -
KZW92_RS05755 1119679..1120053 - 375 WP_000204705.1 CopC domain-containing protein YobA -
KZW92_RS05760 1120192..1120422 + 231 WP_000916763.1 DNA polymerase III subunit theta -
KZW92_RS05765 1120524..1121180 + 657 WP_000011651.1 carbon-nitrogen hydrolase family protein YobB -
KZW92_RS05770 1121204..1121866 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1109920..1125731 15811


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T211316 NZ_CP080235:c1118291-1118188 [Escherichia coli O139:H1]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT211316 NZ_CP080235:1118150-1118421 [Escherichia coli O139:H1]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References