Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2929674..2929945 Replicon chromosome
Accession NZ_CP080233
Organism Escherichia coli O139:H1 strain P15-25

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2929712..2929815 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2929674..2929945 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KZW90_RS14365 2926831..2928270 + 1440 WP_024166480.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
KZW90_RS14370 2928388..2928624 + 237 WP_001295499.1 YebV family protein -
KZW90_RS14375 2928729..2928920 + 192 WP_001296140.1 YebW family protein -
KZW90_RS14380 2928921..2929577 - 657 WP_001520704.1 protein-serine/threonine phosphatase -
- 2929674..2929945 + 272 - - Antitoxin
- 2929712..2929815 - 104 - - Toxin
KZW90_RS14385 2929973..2930314 - 342 WP_000976472.1 YebY family protein -
KZW90_RS14390 2930327..2931199 - 873 WP_000879330.1 copper homeostasis membrane protein CopD -
KZW90_RS14395 2931203..2931577 - 375 WP_000204705.1 CopC domain-containing protein YobA -
KZW90_RS14400 2931716..2931946 + 231 WP_000916763.1 DNA polymerase III subunit theta -
KZW90_RS14405 2932048..2932704 + 657 WP_000011651.1 carbon-nitrogen hydrolase family protein YobB -
KZW90_RS14410 2932728..2933390 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2913834..2953728 39894


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T211296 NZ_CP080233:c2929815-2929712 [Escherichia coli O139:H1]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT211296 NZ_CP080233:2929674-2929945 [Escherichia coli O139:H1]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References