Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2445148..2445419 Replicon chromosome
Accession NZ_CP080172
Organism Escherichia coli strain PK8566

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2445186..2445289 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2445148..2445419 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KZY09_RS12035 2442305..2443744 + 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
KZY09_RS12040 2443862..2444098 + 237 WP_001295499.1 YebV family protein -
KZY09_RS12045 2444203..2444394 + 192 WP_001296140.1 YebW family protein -
KZY09_RS12050 2444395..2445051 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2445148..2445419 + 272 - - Antitoxin
- 2445186..2445289 - 104 - - Toxin
KZY09_RS12055 2445447..2445788 - 342 WP_000976472.1 YebY family protein -
KZY09_RS12060 2445801..2446673 - 873 WP_000879282.1 copper homeostasis membrane protein CopD -
KZY09_RS12065 2446677..2447051 - 375 WP_000204699.1 CopC domain-containing protein YobA -
KZY09_RS12070 2447190..2447420 + 231 WP_000916763.1 DNA polymerase III subunit theta -
KZY09_RS12075 2447522..2448178 + 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
KZY09_RS12080 2448202..2448864 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T211191 NZ_CP080172:c2445289-2445186 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT211191 NZ_CP080172:2445148-2445419 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References