Detailed information of TA system TA021116

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /ElaA-DUF1778
• Location: 1015210..1015979
• Replicon: chromosome
• Accession: NC_006371
• Organism: Photobacterium profundum SS9

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: PBPR_RS22820
• Protein ID: WP_065814487.1
• Coordinates: 1015210..1015710 (-)
• Length: 167 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: PBPR_RS22825
• Protein ID: WP_041395079.1
• Coordinates: 1015707..1015979 (-)
• Length: 91 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PBPR_RS22800	1010879..1011982	-	1104	WP_041395078.1	trypsin-like serine protease	-
PBPR_RS22805	1012228..1013052	+	825	WP_011220952.1	hypothetical protein	-
PBPR_RS22810	1013157..1013744	+	588	WP_041395758.1	nucleotidyltransferase family protein	-
PBPR_RS22815	1013830..1014819	-	990	WP_011220954.1	lipid A deacylase LpxR family protein	-
PBPR_RS22820	1015210..1015710	-	501	WP_065814487.1	GNAT family N-acetyltransferase	Toxin
PBPR_RS22825	1015707..1015979	-	273	WP_041395079.1	DUF1778 domain-containing protein	Antitoxin
PBPR_RS22830	1016333..1017943	+	1611	WP_011220614.1	transposase	-
PBPR_RS22835	1018017..1018862	+	846	WP_011220957.1	sulfurtransferase	-
PBPR_RS22840	1019226..1020053	-	828	WP_041395081.1	phosphate ABC transporter substrate-binding protein	-
PBPR_RS22845	1020184..1020858	-	675	Protein_904	GGDEF domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	1020971..1022251	1280

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (85-150)

Antitoxin

• Vibrio phage ICP1, Orf50 (7-86)

Sequences

Toxin

Protein

• Length: 167 a.a.
• Molecular weight: 18663.58 Da
• Isoelectric Point: 8.8860

>T21116 WP_065814487.1 NC_006371:c1015710-1015210 [Photobacterium profundum SS9]
IMKMVQLDKAKHDRHRFDCGIDALNNYFKIMASQQAKKDNTRTFVLEDINCTEHVIGYYTLAMAPIDLASLPAKLQKKHH
NASSGGLIARLAVDQRYKGNGYGEWLLIDALRKLLMASKTVAFPVVIVDAKDGAEYFYEKYGFTAFQDAENKLFITIADV
RASIGL

Nucleotide

• Length: 501 bp

>T21116 NC_006371:c1015710-1015210 [Photobacterium profundum SS9]
ATAATGAAGATGGTACAATTAGACAAAGCTAAACACGACCGTCATCGCTTTGATTGTGGGATTGATGCGCTAAACAATTA
TTTTAAAATCATGGCGAGTCAACAAGCAAAGAAAGATAATACCCGTACATTTGTGCTTGAAGATATAAACTGTACTGAAC
ATGTTATCGGCTATTACACGCTGGCTATGGCACCGATTGATTTAGCATCACTACCTGCGAAACTACAAAAGAAGCATCAT
AATGCTAGCTCTGGCGGCTTAATCGCAAGGCTTGCCGTTGATCAACGATACAAAGGTAATGGCTATGGCGAATGGTTGCT
GATTGATGCACTTCGAAAATTACTGATGGCGAGCAAAACTGTCGCATTTCCTGTTGTTATCGTTGATGCTAAAGATGGTG
CAGAATACTTCTACGAAAAATATGGCTTCACCGCATTTCAAGATGCTGAAAACAAATTGTTTATCACGATTGCAGATGTA
AGAGCGAGCATTGGTCTTTAA

Antitoxin

Protein

• Length: 91 a.a.
• Molecular weight: 9854.44 Da
• Isoelectric Point: 9.8629

>AT21116 WP_041395079.1 NC_006371:c1015979-1015707 [Photobacterium profundum SS9]
MATALPRITARVDIDTQELLSQAAAIAGMSSINSFVLSAAVEKAKQIMERERALKLSQRDAMMLMDALDEPAKPNARLQH
AAARYKDKAQ

Nucleotide

• Length: 273 bp

>AT21116 NC_006371:c1015979-1015707 [Photobacterium profundum SS9]
ATGGCTACAGCATTACCCCGTATCACTGCCCGTGTAGACATTGATACTCAAGAATTACTATCACAAGCAGCAGCTATCGC
TGGTATGTCTAGCATTAACTCGTTTGTTCTTAGCGCTGCTGTTGAAAAAGCTAAGCAAATAATGGAGCGAGAACGAGCAC
TTAAACTAAGCCAACGCGACGCTATGATGCTTATGGATGCTCTTGATGAACCAGCAAAACCTAATGCTCGTTTGCAGCAT
GCTGCAGCTCGTTACAAGGACAAAGCGCAATAA