Detailed information of TA system TA021113

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 1707628..1708187
• Replicon: chromosome
• Accession: NC_006370
• Organism: Photobacterium profundum SS9

Toxin (Protein)

• Gene name: relE
• Uniprot ID: Q6LS09
• Locus tag: PBPR_RS07665
• Protein ID: WP_011218238.1
• Coordinates: 1707909..1708187 (+)
• Length: 93 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: Q6LS10
• Locus tag: PBPR_RS07660
• Protein ID: WP_011218237.1
• Coordinates: 1707628..1707912 (+)
• Length: 95 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PBPR_RS07635	1703198..1703710	-	513	WP_011218232.1	hypothetical protein	-
PBPR_RS07640	1704040..1704411	+	372	WP_011218233.1	hypothetical protein	-
PBPR_RS07645	1704552..1705094	-	543	WP_041394112.1	ParB N-terminal domain-containing protein	-
PBPR_RS07650	1705166..1705840	-	675	WP_041394114.1	hypothetical protein	-
PBPR_RS07655	1706054..1707112	-	1059	WP_065814470.1	hypothetical protein	-
PBPR_RS07660	1707628..1707912	+	285	WP_011218237.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
PBPR_RS07665	1707909..1708187	+	279	WP_011218238.1	type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family	Toxin
PBPR_RS07670	1708331..1708660	-	330	WP_041394116.1	hypothetical protein	-
PBPR_RS07675	1708657..1709028	-	372	WP_011218240.1	hypothetical protein	-
PBPR_RS07680	1709030..1709806	-	777	WP_041394118.1	hypothetical protein	-
PBPR_RS30570	1710241..1710342	-	102	WP_157134306.1	MetS family NSS transporter small subunit	-
PBPR_RS07690	1710345..1711826	-	1482	WP_041394122.1	sodium-dependent transporter	-
PBPR_RS07695	1712217..1712816	-	600	WP_011218243.1	hypothetical protein	-
PBPR_RS30575	1712962..1713051	+	90	WP_041394124.1	YnhF family membrane protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (2-89)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (4-70)

Sequences

Toxin

Protein

• Length: 93 a.a.
• Molecular weight: 11035.71 Da
• Isoelectric Point: 4.3995

>T21113 WP_011218238.1 NC_006370:1707909-1708187 [Photobacterium profundum SS9]
MILWEEESLNDREKIFEFLYDFYPEAAERTDQIIEDKVENLLDHPLMGEQREGIRGRLLIIPEVSMIVSYWVEGSIIRIM
RVLHQKQKFPAE

Nucleotide

• Length: 279 bp

>T21113 NC_006370:1707909-1708187 [Photobacterium profundum SS9]
ATGATACTTTGGGAAGAAGAGTCACTTAACGATCGTGAGAAAATTTTTGAATTTCTCTATGACTTTTATCCCGAAGCTGC
TGAACGAACTGACCAGATTATTGAAGACAAAGTCGAAAACTTACTCGATCACCCTTTAATGGGCGAACAAAGAGAAGGTA
TTCGAGGTCGTTTACTCATTATTCCAGAGGTATCAATGATTGTATCTTACTGGGTTGAAGGCTCAATCATTCGTATAATG
CGCGTACTGCATCAGAAGCAAAAATTTCCTGCAGAGTAG

Antitoxin

Protein

• Length: 95 a.a.
• Molecular weight: 10774.15 Da
• Isoelectric Point: 5.8857

>AT21113 WP_011218237.1 NC_006370:1707628-1707912 [Photobacterium profundum SS9]
MDTIIQFRVDEETKRLAQLMAESQGSTLSDACRELIEQLAEQQRKTMTHDAWLTEQVNAAFEKFDSGKAVFIEQQDAKAR
MDARKAKIRNRGQA

Nucleotide

• Length: 285 bp

>AT21113 NC_006370:1707628-1707912 [Photobacterium profundum SS9]
ATGGACACTATAATCCAGTTTCGTGTTGATGAAGAAACTAAACGTTTGGCTCAGTTAATGGCAGAAAGCCAAGGTAGTAC
ACTGAGTGATGCTTGCCGTGAACTGATAGAGCAACTAGCCGAACAGCAACGTAAAACAATGACTCATGATGCTTGGCTTA
CAGAGCAAGTAAACGCTGCTTTTGAAAAATTTGATTCAGGAAAAGCGGTATTCATTGAACAGCAAGATGCAAAAGCACGT
ATGGATGCACGCAAAGCTAAGATTCGAAATCGAGGTCAAGCATGA

Structures

Toxin

• AlphaFold DB: Q6LS09

Antitoxin

• AlphaFold DB: Q6LS10