Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2218201..2218472 Replicon chromosome
Accession NZ_CP080155
Organism Escherichia coli strain PK8261

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2218331..2218434 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2218201..2218472 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KZY07_RS10550 2214756..2215418 - 663 WP_000944256.1 exodeoxyribonuclease X -
KZY07_RS10555 2215442..2216098 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein YobB -
KZY07_RS10560 2216200..2216430 - 231 WP_000916763.1 DNA polymerase III subunit theta -
KZY07_RS10565 2216569..2216943 + 375 WP_000204705.1 CopC domain-containing protein YobA -
KZY07_RS10570 2216947..2217819 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
KZY07_RS10575 2217832..2218173 + 342 WP_000976481.1 YebY family protein -
- 2218201..2218472 - 272 - - Antitoxin
- 2218331..2218434 + 104 - - Toxin
KZY07_RS10580 2218569..2219225 + 657 WP_001546849.1 protein-serine/threonine phosphatase -
KZY07_RS10585 2219226..2219417 - 192 WP_001296140.1 YebW family protein -
KZY07_RS10590 2219522..2219758 - 237 WP_001295499.1 YebV family protein -
KZY07_RS10595 2219876..2221315 - 1440 WP_001309555.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2210891..2235022 24131


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T211102 NZ_CP080155:2218331-2218434 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT211102 NZ_CP080155:c2218472-2218201 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References