Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1170521..1170792 Replicon chromosome
Accession NZ_CP080146
Organism Escherichia coli strain PK8276

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1170651..1170754 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1170521..1170792 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KZY06_RS05440 1167077..1167739 - 663 WP_000944256.1 exodeoxyribonuclease X -
KZY06_RS05445 1167763..1168419 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein YobB -
KZY06_RS05450 1168521..1168751 - 231 WP_000916763.1 DNA polymerase III subunit theta -
KZY06_RS05455 1168890..1169264 + 375 WP_000168747.1 CopC domain-containing protein YobA -
KZY06_RS05460 1169268..1170140 + 873 WP_000879294.1 copper homeostasis membrane protein CopD -
KZY06_RS05465 1170153..1170494 + 342 WP_000976472.1 YebY family protein -
- 1170521..1170792 - 272 - - Antitoxin
- 1170651..1170754 + 104 - - Toxin
KZY06_RS05470 1170889..1171545 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
KZY06_RS05475 1171546..1171737 - 192 WP_001296140.1 YebW family protein -
KZY06_RS05480 1171842..1172078 - 237 WP_001295499.1 YebV family protein -
KZY06_RS05485 1172196..1173635 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T211061 NZ_CP080146:1170651-1170754 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT211061 NZ_CP080146:c1170792-1170521 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTAGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References