Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2224279..2224547 Replicon chromosome
Accession NZ_CP080117
Organism Escherichia coli strain OV24

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2224407..2224509 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2224279..2224547 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KZX74_RS10645 2220832..2221494 - 663 WP_000944256.1 exodeoxyribonuclease X -
KZX74_RS10650 2221518..2222174 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
KZX74_RS10655 2222276..2222506 - 231 WP_000916763.1 DNA polymerase III subunit theta -
KZX74_RS10660 2222645..2223019 + 375 WP_000168747.1 CopC domain-containing protein YobA -
KZX74_RS10665 2223023..2223895 + 873 WP_000879317.1 copper homeostasis membrane protein CopD -
KZX74_RS10670 2223908..2224249 + 342 WP_000976472.1 YebY family protein -
- 2224279..2224547 - 269 - - Antitoxin
- 2224407..2224509 + 103 - - Toxin
KZX74_RS10675 2224644..2225300 + 657 WP_000812745.1 protein-serine/threonine phosphatase -
KZX74_RS10680 2225301..2225492 - 192 WP_001296140.1 YebW family protein -
KZX74_RS10685 2225597..2225833 - 237 WP_001295499.1 YebV family protein -
KZX74_RS10690 2225950..2227389 - 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T210827 NZ_CP080117:2224407-2224509 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT210827 NZ_CP080117:c2224547-2224279 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References