Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/YafN(antitoxin) |
| Location | 2884508..2885073 | Replicon | chromosome |
| Accession | NZ_CP080098 | ||
| Organism | Vibrio harveyi strain | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | KZR01_RS23740 | Protein ID | WP_259556173.1 |
| Coordinates | 2884508..2884795 (-) | Length | 96 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | U3BLE1 |
| Locus tag | KZR01_RS23745 | Protein ID | WP_000086647.1 |
| Coordinates | 2884792..2885073 (-) | Length | 94 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KZR01_RS23700 | 2880386..2880895 | + | 510 | WP_053053932.1 | hypothetical protein | - |
| KZR01_RS23705 | 2881434..2881985 | - | 552 | WP_259556170.1 | hypothetical protein | - |
| KZR01_RS23710 | 2882150..2882623 | - | 474 | WP_227740521.1 | DUF4476 domain-containing protein | - |
| KZR01_RS23715 | 2882658..2882747 | - | 90 | WP_077672554.1 | DUF3265 domain-containing protein | - |
| KZR01_RS23720 | 2882805..2882954 | - | 150 | WP_259556171.1 | hypothetical protein | - |
| KZR01_RS23725 | 2883067..2883152 | - | 86 | Protein_2604 | DUF3265 domain-containing protein | - |
| KZR01_RS23730 | 2883181..2883525 | - | 345 | WP_259556172.1 | antibiotic biosynthesis monooxygenase | - |
| KZR01_RS23735 | 2883651..2883743 | - | 93 | WP_079757365.1 | DUF3265 domain-containing protein | - |
| KZR01_RS23740 | 2884508..2884795 | - | 288 | WP_259556173.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| KZR01_RS23745 | 2884792..2885073 | - | 282 | WP_000086647.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| KZR01_RS23750 | 2885218..2885295 | - | 78 | Protein_2609 | DUF3265 domain-containing protein | - |
| KZR01_RS23755 | 2885292..2885594 | - | 303 | WP_259556174.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| KZR01_RS23760 | 2885582..2885840 | - | 259 | Protein_2611 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| KZR01_RS23765 | 2886830..2887156 | - | 327 | WP_259556175.1 | hypothetical protein | - |
| KZR01_RS23770 | 2887252..2887530 | - | 279 | WP_259556176.1 | hypothetical protein | - |
| KZR01_RS23775 | 2887558..2887650 | - | 93 | WP_072616277.1 | DUF3265 domain-containing protein | - |
| KZR01_RS23780 | 2888126..2888536 | - | 411 | WP_259556177.1 | bacteriophage abortive infection AbiH family protein | - |
| KZR01_RS23785 | 2888660..2888749 | - | 90 | WP_259557722.1 | DUF3265 domain-containing protein | - |
| KZR01_RS23790 | 2888778..2889196 | - | 419 | Protein_2617 | GNAT family N-acetyltransferase | - |
| KZR01_RS23795 | 2889325..2889744 | - | 420 | WP_005536771.1 | hypothetical protein | - |
| KZR01_RS23800 | 2889780..2889872 | - | 93 | WP_079740779.1 | DUF3265 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 2862448..2962652 | 100204 | |
| - | inside | Integron | - | - | 2868257..2962652 | 94395 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 96 a.a. Molecular weight: 10940.59 Da Isoelectric Point: 5.5379
>T210753 WP_259556173.1 NZ_CP080098:c2884795-2884508 [Vibrio harveyi]
MKVVWSPLALQKLGDAAEFISLDNPPAAERWVNGVFDKTELLGSMPEMGRFVPEMPHTNYREIIFGHYRIIYSLSHEIRV
LTVRNCHQILSEDDV
MKVVWSPLALQKLGDAAEFISLDNPPAAERWVNGVFDKTELLGSMPEMGRFVPEMPHTNYREIIFGHYRIIYSLSHEIRV
LTVRNCHQILSEDDV
Download Length: 288 bp
>T210753 NZ_CP104613:275102-275275 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG
Antitoxin
Download Length: 94 a.a. Molecular weight: 10398.91 Da Isoelectric Point: 5.8650
>AT210753 WP_000086647.1 NZ_CP080098:c2885073-2884792 [Vibrio harveyi]
MSRIHFDQDIQPLSEFRAGVASYIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLASGLGVSN
DDARAQVLGRIKK
MSRIHFDQDIQPLSEFRAGVASYIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLASGLGVSN
DDARAQVLGRIKK
Download Length: 282 bp
>AT210753 NZ_CP104613:274778-275074 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAATTTCTCCTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAACT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTTAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAATTTCTCCTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAACT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTTAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|