Detailed information of TA system TA021068

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): paaR-paaA-parE/-
• Location: 1837033..1837529
• Replicon: chromosome
• Accession: NC_005956
• Organism: Bartonella henselae str. Houston-1

Toxin (Protein)

• Gene name: parE_1
• Uniprot ID: -
• Locus tag: AYT27_RS08335
• Protein ID: WP_197536999.1
• Coordinates: 1837290..1837529 (+)
• Length: 80 a.a.

Antitoxin (Protein)

• Gene name: paaA
• Uniprot ID: -
• Locus tag: AYT27_RS08330
• Protein ID: WP_034448465.1
• Coordinates: 1837033..1837242 (+)
• Length: 70 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AYT27_RS08310	1832534..1833034	-	501	Protein_1483	transcriptional regulator	-
AYT27_RS08315	1833683..1834354	-	672	WP_011181356.1	VUT family protein	-
AYT27_RS08320	1834468..1834761	-	294	WP_011181357.1	50S ribosomal protein L28	-
AYT27_RS08325	1835040..1835825	+	786	WP_011181358.1	SURF1 family protein	-
AYT27_RS08330	1837033..1837242	+	210	WP_034448465.1	hypothetical protein	Antitoxin
AYT27_RS08335	1837290..1837529	+	240	WP_197536999.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
AYT27_RS09045	1837755..1837911	+	157	Protein_1489	DUF4102 domain-containing protein	-
AYT27_RS08340	1839595..1839750	-	156	WP_011181359.1	DUF1127 domain-containing protein	-
AYT27_RS08345	1840031..1841647	-	1617	WP_011181360.1	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (1-75)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 80 a.a.
• Molecular weight: 9317.94 Da
• Isoelectric Point: 10.0545

>T21068 WP_197536999.1 NC_005956:1837290-1837529 [Bartonella henselae str. Houston-1]
ILSYIARENPFAARRMKKQLEASVLPLSEHPYLYQKSERVLKLREIVAHPNYLILYQVTVNQIEIVTVVHTRREFPVSL

Nucleotide

• Length: 240 bp

>T21068 NC_005956:1837290-1837529 [Bartonella henselae str. Houston-1]
ATTTTATCTTACATTGCTCGTGAAAATCCATTTGCTGCGCGACGAATGAAAAAACAGCTGGAAGCGTCCGTGTTACCTTT
ATCCGAGCATCCATATTTGTATCAAAAAAGTGAAAGAGTATTAAAGCTAAGAGAAATTGTAGCCCATCCAAATTATCTTA
TATTGTATCAAGTGACCGTAAATCAAATTGAGATTGTTACTGTAGTACATACTCGGCGTGAGTTTCCTGTTTCTCTGTGA

Antitoxin

Protein

• Length: 70 a.a.
• Molecular weight: 7954.96 Da
• Isoelectric Point: 4.3201

>AT21068 WP_034448465.1 NC_005956:1837033-1837242 [Bartonella henselae str. Houston-1]
IHDQYKGKTAFSLLVSEFEIAEQELSYTDWLRNKVAKSLANLHPVIPHDEVMAEMEAVRDQIVAEQEEL

Nucleotide

• Length: 210 bp

>AT21068 NC_005956:1837033-1837242 [Bartonella henselae str. Houston-1]
ATCCATGATCAATATAAAGGAAAGACTGCTTTTTCTCTACTCGTTTCAGAATTTGAAATAGCCGAGCAGGAACTTAGTTA
TACTGATTGGTTGCGTAACAAGGTAGCAAAGAGTCTTGCTAATCTGCATCCTGTCATTCCGCATGACGAGGTTATGGCTG
AAATGGAAGCGGTAAGAGATCAGATTGTCGCCGAGCAGGAAGAGTTGTAG