210447

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 1840692..1841459 Replicon chromosome
Accession NZ_CP079984
Organism Macrococcus bohemicus strain 19Msa0383

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag KYI13_RS09635 Protein ID WP_165958672.1
Coordinates 1840692..1840835 (-) Length 48 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag KYI13_RS09640 Protein ID WP_096075978.1
Coordinates 1840848..1841459 (-) Length 204 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KYI13_RS09625 (KYI13_09630) 1837633..1839165 - 1533 WP_096075980.1 exopolyphosphatase -
KYI13_RS09630 (KYI13_09635) 1839196..1840581 - 1386 WP_096075979.1 class II fumarate hydratase -
KYI13_RS09635 (KYI13_09640) 1840692..1840835 - 144 WP_165958672.1 SAS053 family protein Toxin
KYI13_RS09640 (KYI13_09645) 1840848..1841459 - 612 WP_096075978.1 glucosamine-6-phosphate isomerase Antitoxin
KYI13_RS09645 (KYI13_09650) 1841790..1842527 - 738 WP_219497590.1 oxygen-insensitive NADPH nitroreductase -
KYI13_RS09650 (KYI13_09655) 1842540..1843013 - 474 WP_096075976.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
KYI13_RS09655 (KYI13_09660) 1843014..1844138 - 1125 WP_203545697.1 tRNA epoxyqueuosine(34) reductase QueG -
KYI13_RS09660 (KYI13_09665) 1844289..1845011 - 723 WP_096075974.1 amino acid ABC transporter ATP-binding protein -
KYI13_RS09665 (KYI13_09670) 1845004..1846410 - 1407 WP_096078059.1 ABC transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-91)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5413.64 Da        Isoelectric Point: 3.6118

>T210447 WP_165958672.1 NZ_CP079984:c1840835-1840692 [Macrococcus bohemicus]
MSTSHDNKNEMVTDFDDVVELGKEMEQISEQNAEAREEGQEQEDDPQ

Download         Length: 144 bp

>T210447 NZ_CP104522:c53909-53631 [Escherichia coli]
ATGGAGATATTCTGGACCATGCTGGCCAGCCAGGACAGGAAGCGCATTCGTGAGTACATTGCGGAGCAGAACCTGATGGC
CGCCATTGAACTGGACGAACGGATTGGTTATTCAGCCAGCAGCCTGGCCGGGCAGCCGTATAAAGGCCGCAACGGTCGTG
TGGAAGGTACCCGGGAACTGGTTATTCACCCGCATTTTGTTCTGGTTTATGAGGTCGACAGCCAGTGGGGAAAAGTGTAT
ATCCTGCGTGTATTGCATACTGCACAGAAGTGGCCATAG

Antitoxin


Download         Length: 204 a.a.        Molecular weight: 22525.50 Da        Isoelectric Point: 5.3614

>AT210447 WP_096075978.1 NZ_CP079984:c1841459-1840848 [Macrococcus bohemicus]
MAMNFKIFEDKLTVSNYVADLFRKQMSNNPTSIIATALGDEAGHVIAELKANIARNPVETSQIHIFDYDKLRGDYGTVGI
VDKQYHEATGKDIMELIKDEAKTKENKGKLTTLFATITQDGSVGYKEINQDNDKGLRSAREIIIVLTGADKASIVEKLYN
TEAGGNFEAANLKTHRMVNVILDDAAAAGLPQDIREYYFQKFA

Download         Length: 612 bp

>AT210447 NZ_CP104522:c54178-53909 [Escherichia coli]
ATGGCACAGGTTAATATGAGTTTAAGAATTGACGCTGAACTGAAGGATGCTTTTATGGCCGCTGCAAAAAGCATGGACCG
TAATGGCTCTCAGTTAATCCGGGATTTTATGCGCCAGACCGTGGAACGGCAGCATAATACCTGGTTCCGTGACCAGGTTG
AGGCAGGACGTCAGCAACTCGAGCGCGGCGATGTGCTTCCCCATGACATGGTCGAATCTTCCGCTGCTGCATGGCGGGAT
GAAATGAGCAGGAAAGTCGCCGGTAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References