Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 1868871..1869638 Replicon chromosome
Accession NZ_CP079981
Organism Macrococcus bohemicus strain 19Msa0936

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag KYI11_RS09710 Protein ID WP_165958672.1
Coordinates 1868871..1869014 (-) Length 48 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag KYI11_RS09715 Protein ID WP_096075978.1
Coordinates 1869027..1869638 (-) Length 204 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KYI11_RS09700 (KYI11_09710) 1865812..1867344 - 1533 WP_096075980.1 exopolyphosphatase -
KYI11_RS09705 (KYI11_09715) 1867375..1868760 - 1386 WP_096075979.1 class II fumarate hydratase -
KYI11_RS09710 (KYI11_09720) 1868871..1869014 - 144 WP_165958672.1 SAS053 family protein Toxin
KYI11_RS09715 (KYI11_09725) 1869027..1869638 - 612 WP_096075978.1 glucosamine-6-phosphate isomerase Antitoxin
KYI11_RS09720 (KYI11_09730) 1869969..1870706 - 738 WP_219502703.1 oxygen-insensitive NADPH nitroreductase -
KYI11_RS09725 (KYI11_09735) 1870719..1871192 - 474 WP_096075976.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
KYI11_RS09730 (KYI11_09740) 1871193..1872317 - 1125 WP_203545697.1 tRNA epoxyqueuosine(34) reductase QueG -
KYI11_RS09735 (KYI11_09745) 1872468..1873190 - 723 WP_096075974.1 amino acid ABC transporter ATP-binding protein -
KYI11_RS09740 (KYI11_09750) 1873183..1874589 - 1407 WP_096078059.1 ABC transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5413.64 Da        Isoelectric Point: 3.6118

>T210444 WP_165958672.1 NZ_CP079981:c1869014-1868871 [Macrococcus bohemicus]
MSTSHDNKNEMVTDFDDVVELGKEMEQISEQNAEAREEGQEQEDDPQ

Download         Length: 144 bp

>T210444 NZ_CP104521:c4525303-4525196 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGCATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin


Download         Length: 204 a.a.        Molecular weight: 22525.50 Da        Isoelectric Point: 5.3614

>AT210444 WP_096075978.1 NZ_CP079981:c1869638-1869027 [Macrococcus bohemicus]
MAMNFKIFEDKLTVSNYVADLFRKQMSNNPTSIIATALGDEAGHVIAELKANIARNPVETSQIHIFDYDKLRGDYGTVGI
VDKQYHEATGKDIMELIKDEAKTKENKGKLTTLFATITQDGSVGYKEINQDNDKGLRSAREIIIVLTGADKASIVEKLYN
TEAGGNFEAANLKTHRMVNVILDDAAAAGLPQDIREYYFQKFA

Download         Length: 612 bp

>AT210444 NZ_CP104521:4525351-4525417 [Escherichia coli]
GGTCTAGATGCAAGAATGGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References