Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
| Location | 1107979..1109021 | Replicon | chromosome |
| Accession | NZ_CP079940 | ||
| Organism | Achromobacter sp. ES-001 | ||
Toxin (Protein)
| Gene name | PP_4152 | Uniprot ID | - |
| Locus tag | KYT87_RS04895 | Protein ID | WP_003109777.1 |
| Coordinates | 1107979..1108554 (-) | Length | 192 a.a. |
Antitoxin (Protein)
| Gene name | PP_4151 | Uniprot ID | I3TV68 |
| Locus tag | KYT87_RS04900 | Protein ID | WP_003050245.1 |
| Coordinates | 1108551..1109021 (-) | Length | 157 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KYT87_RS04870 (KYT87_04870) | 1104417..1105142 | - | 726 | WP_003050273.1 | CBASS effector endonuclease NucC | - |
| KYT87_RS04875 (KYT87_04875) | 1105181..1106083 | - | 903 | WP_003105624.1 | CBASS oligonucleotide cyclase | - |
| KYT87_RS04880 (KYT87_04880) | 1106083..1106583 | - | 501 | WP_003090159.1 | type III CBASS phage resistance system CD-NTase-associated protein Cap7 | - |
| KYT87_RS04885 (KYT87_04885) | 1106580..1107050 | - | 471 | WP_003105626.1 | type III CBASS phage resistance system CD-NTase-associated protein Cap8 | - |
| KYT87_RS04890 (KYT87_04890) | 1107047..1107961 | - | 915 | WP_003105629.1 | AAA family ATPase | - |
| KYT87_RS04895 (KYT87_04895) | 1107979..1108554 | - | 576 | WP_003109777.1 | PIN domain-containing protein | Toxin |
| KYT87_RS04900 (KYT87_04900) | 1108551..1109021 | - | 471 | WP_003050245.1 | helix-turn-helix domain-containing protein | Antitoxin |
| KYT87_RS04905 (KYT87_04905) | 1109225..1109608 | + | 384 | WP_003105635.1 | RAQPRD family integrative conjugative element protein | - |
| KYT87_RS04910 (KYT87_04910) | 1109605..1109838 | + | 234 | WP_003050225.1 | TIGR03758 family integrating conjugative element protein | - |
| KYT87_RS04915 (KYT87_04915) | 1109855..1110214 | + | 360 | WP_003090173.1 | TIGR03745 family integrating conjugative element membrane protein | - |
| KYT87_RS04920 (KYT87_04920) | 1110226..1110624 | + | 399 | WP_003105639.1 | TIGR03750 family conjugal transfer protein | - |
| KYT87_RS04925 (KYT87_04925) | 1110621..1111313 | + | 693 | WP_003105641.1 | TIGR03746 family integrating conjugative element protein | - |
| KYT87_RS04930 (KYT87_04930) | 1111310..1112221 | + | 912 | WP_003105643.1 | TIGR03749 family integrating conjugative element protein | - |
| KYT87_RS04935 (KYT87_04935) | 1112211..1113629 | + | 1419 | WP_003109776.1 | TIGR03752 family integrating conjugative element protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 192 a.a. Molecular weight: 21644.79 Da Isoelectric Point: 5.6172
>T210427 WP_003109777.1 NZ_CP079940:c1108554-1107979 [Achromobacter sp. ES-001]
MRHSPFTAVYDACVLYPAPLRDFLMWLGLSGRFRARWSQAIHEEWKRNLLINRPDLTRVQVDRTSDLMDRAIPDGLVEGY
EALVAGLTLPDPDDRHVLAAAIRCGASVIVTFNERDFPNDLLAPYGIESQHPDEFVDNLLDLDAAAVVSAAQRQRAQLKH
PPIEVDRYLEILLRQGLVQTTKVLATYRTIL
MRHSPFTAVYDACVLYPAPLRDFLMWLGLSGRFRARWSQAIHEEWKRNLLINRPDLTRVQVDRTSDLMDRAIPDGLVEGY
EALVAGLTLPDPDDRHVLAAAIRCGASVIVTFNERDFPNDLLAPYGIESQHPDEFVDNLLDLDAAAVVSAAQRQRAQLKH
PPIEVDRYLEILLRQGLVQTTKVLATYRTIL
Download Length: 576 bp
>T210427 NZ_CP104521:c1145228-1145010 [Escherichia coli]
ATGTCCGAAAAACCTTTAACAAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA
ATGTCCGAAAAACCTTTAACAAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA
Antitoxin
Download Length: 157 a.a. Molecular weight: 17245.62 Da Isoelectric Point: 6.3803
>AT210427 WP_003050245.1 NZ_CP079940:c1109021-1108551 [Achromobacter sp. ES-001]
MTTATAQSKMTLPAAGEVKAAVQGQRALAAYLATQFETQHIQIFDDHKQAHQVELPTSALRLLVDILAELADGNAVKVVP
VHAELTTQEAADLLNVSRPHFVKLLEDGVLAFHRTGKHRRVRFADLMQYKEARERASEQAMAELAQQSQELGMGYE
MTTATAQSKMTLPAAGEVKAAVQGQRALAAYLATQFETQHIQIFDDHKQAHQVELPTSALRLLVDILAELADGNAVKVVP
VHAELTTQEAADLLNVSRPHFVKLLEDGVLAFHRTGKHRRVRFADLMQYKEARERASEQAMAELAQQSQELGMGYE
Download Length: 471 bp
>AT210427 NZ_CP104521:c1145628-1145254 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCGCAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGTCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGCAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG
ATGGATGAATACTCACCCAAAAGACATGATATCGCGCAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGTCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGCAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|