Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/-
Location 890743..891284 Replicon chromosome
Accession NZ_CP079926
Organism Caulobacter vibrioides strain CB S2B lysogen

Toxin (Protein)


Gene name relE Uniprot ID Q9AA09
Locus tag KZH45_RS04180 Protein ID WP_010918687.1
Coordinates 890743..891024 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q9AA08
Locus tag KZH45_RS04185 Protein ID WP_010918688.1
Coordinates 891021..891284 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KZH45_RS04165 (KZH45_04165) 885825..887441 - 1617 WP_012640065.1 carboxylesterase/lipase family protein -
KZH45_RS04170 (KZH45_04170) 887531..889255 - 1725 WP_010918685.1 hypothetical protein -
KZH45_RS04175 (KZH45_04175) 889339..890667 - 1329 WP_010918686.1 mannanase -
KZH45_RS04180 (KZH45_04180) 890743..891024 - 282 WP_010918687.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KZH45_RS04185 (KZH45_04185) 891021..891284 - 264 WP_010918688.1 type II toxin-antitoxin system antitoxin RelB1 Antitoxin
KZH45_RS04190 (KZH45_04190) 891323..894436 - 3114 WP_272938710.1 bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase PutA -
KZH45_RS04195 (KZH45_04195) 894497..894658 + 162 WP_024265629.1 hypothetical protein -
KZH45_RS04200 (KZH45_04200) 894858..895325 + 468 WP_010918690.1 Lrp/AsnC ligand binding domain-containing protein -
KZH45_RS04205 (KZH45_04205) 895352..895516 - 165 WP_024265630.1 leucine-responsive regulatory protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10486.14 Da        Isoelectric Point: 11.7926

>T210399 WP_010918687.1 NZ_CP079926:c891024-890743 [Caulobacter vibrioides]
MTFTVLVSVRAKRDFNRLIVWLVERDPRAAARLGPLLEAALDSLTEAPSRGRSVGPTTREISIPFGQSAYVIRYRLLGSS
VHVTRIWHGLEQR

Download         Length: 282 bp

>T210399 NZ_CP104516:923484-923591 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACTTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9198.31 Da        Isoelectric Point: 4.2560

>AT210399 WP_010918688.1 NZ_CP079926:c891284-891021 [Caulobacter vibrioides]
MADGFDIHIDQEQAARLKVVADRLGMSVSEYAVALIDAGLTGAAPKAIDPDPAIDEAIADAIERGDEPAISRDEFRAHIR
RVTAGLG

Download         Length: 264 bp

>AT210399 NZ_CP104516:c923437-923371 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q9AA09

Antitoxin

Source ID Structure
AlphaFold DB Q9AA08

References