Detailed information of TA system TA021038

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-RHH
• Location: 2058304..2058817
• Replicon: chromosome
• Accession: NC_005773
• Organism: Pseudomonas syringae pv. phaseolicola 1448A

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: PSPPH_RS08870
• Protein ID: WP_004658391.1
• Coordinates: 2058304..2058588 (-)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: Q48KT0
• Locus tag: PSPPH_RS08875
• Protein ID: WP_011168200.1
• Coordinates: 2058578..2058817 (-)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PSPPH_RS08855	2054447..2056375	+	1929	WP_004665865.1	methyl-accepting chemotaxis protein	-
PSPPH_RS08860	2056406..2057338	-	933	WP_041924491.1	DMT family transporter	-
PSPPH_RS08865	2057413..2058267	+	855	WP_004658390.1	LysR family transcriptional regulator	-
PSPPH_RS08870	2058304..2058588	-	285	WP_004658391.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
PSPPH_RS08875	2058578..2058817	-	240	WP_011168200.1	CopG family ribbon-helix-helix protein	Antitoxin
PSPPH_RS08880	2058977..2059993	-	1017	WP_011168201.1	1-aminocyclopropane-1-carboxylate deaminase	-
PSPPH_RS08885	2060180..2060686	+	507	WP_004658394.1	Lrp/AsnC family transcriptional regulator	-
PSPPH_RS08890	2060836..2061744	+	909	WP_011168203.1	DUF808 domain-containing protein	-
PSPPH_RS08895	2061923..2062695	-	773	Protein_1772	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-89)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-41)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10647.31 Da
• Isoelectric Point: 10.4249

>T21038 WP_004658391.1 NC_005773:c2058588-2058304 [Pseudomonas savastanoi pv. phaseolicola 1448A]
MQVEWLKTALKNLDEEAAYIAQDNPAAAAAFVKAIQSSVTQLASFPAMGREGRIAGTREWPLPDLPYLIPYRIRSGRLQV
LRIFHTRRQSPPVW

Nucleotide

• Length: 285 bp

>T21038 NC_005773:c2058588-2058304 [Pseudomonas savastanoi pv. phaseolicola 1448A]
ATGCAGGTTGAGTGGCTTAAAACGGCGCTAAAGAATCTGGATGAGGAGGCAGCGTATATCGCACAGGACAATCCAGCTGC
TGCCGCAGCTTTCGTGAAAGCAATTCAATCAAGCGTGACGCAGCTCGCGAGCTTTCCCGCCATGGGCCGGGAAGGACGGA
TTGCCGGAACCAGAGAATGGCCTCTGCCAGACCTGCCTTACCTGATTCCATATCGCATCCGTAGCGGCCGGCTACAGGTT
CTAAGGATTTTCCACACCAGAAGACAATCGCCCCCCGTGTGGTGA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 8688.78 Da
• Isoelectric Point: 4.4354

>AT21038 WP_011168200.1 NC_005773:c2058817-2058578 [Pseudomonas savastanoi pv. phaseolicola 1448A]
MSTMSLRLPDEMADTLAHLAKATGRSKSFLALDALREYLTREAWQIAEIQRAIEEADAGEFASTEDVKAVMDKWSGNAG

Nucleotide

• Length: 240 bp

>AT21038 NC_005773:c2058817-2058578 [Pseudomonas savastanoi pv. phaseolicola 1448A]
ATGTCCACAATGTCTCTACGTCTGCCGGACGAAATGGCGGATACCCTTGCACACCTTGCAAAGGCGACCGGGCGCAGCAA
GTCATTTTTGGCCCTCGACGCGCTCCGCGAATACCTGACTCGCGAGGCATGGCAGATTGCCGAAATTCAGCGCGCGATTG
AAGAAGCCGACGCTGGCGAGTTCGCCAGTACAGAGGACGTAAAAGCTGTCATGGACAAATGGTCTGGCAATGCAGGTTGA

Structures

Antitoxin

• AlphaFold DB: A0A3M6AYQ8