Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 186131..186650 Replicon chromosome
Accession NC_005773
Organism Pseudomonas syringae pv. phaseolicola 1448A

Toxin (Protein)


Gene name relE Uniprot ID Q48Q48
Locus tag PSPPH_RS00795 Protein ID WP_002551445.1
Coordinates 186360..186650 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S6UWW5
Locus tag PSPPH_RS00790 Protein ID WP_002551444.1
Coordinates 186131..186370 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSPPH_RS00770 182883..184157 + 1275 WP_004667253.1 OprD family porin -
PSPPH_RS00775 184191..184685 - 495 WP_004667254.1 hypothetical protein -
PSPPH_RS00780 184846..185394 + 549 WP_004667255.1 GNAT family N-acetyltransferase -
PSPPH_RS00785 185495..185968 + 474 WP_011167361.1 GNAT family N-acetyltransferase -
PSPPH_RS00790 186131..186370 + 240 WP_002551444.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PSPPH_RS00795 186360..186650 + 291 WP_002551445.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PSPPH_RS00800 186767..187144 + 378 Protein_158 transposase -
PSPPH_RS00805 187305..188108 - 804 WP_011167363.1 IS21-like element ISPsy20 family helper ATPase IstB -
PSPPH_RS00810 188101..188691 - 591 Protein_160 IS21 family transposase -
PSPPH_RS00820 189206..189700 + 495 WP_011167365.1 type VI secretion system tube protein Hcp -
PSPPH_RS00825 189713..190558 + 846 WP_011167366.1 hypothetical protein -
PSPPH_RS00830 190569..190940 + 372 WP_019740508.1 hypothetical protein -
PSPPH_RS00835 191079..191360 + 282 WP_041924381.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11316.19 Da        Isoelectric Point: 10.2579

>T21037 WP_002551445.1 NC_005773:186360-186650 [Pseudomonas savastanoi pv. phaseolicola 1448A]
MTYNLEFDARALKEWHKLGDTVRQQLKKKLATILVAPRVEANRLHALPDCYKIKLRSSGYRLVYQVIDQEVVVFVVAVDK
REREEVYRKATDRLGR

Download         Length: 291 bp

>T21037 NC_005773:186360-186650 [Pseudomonas savastanoi pv. phaseolicola 1448A]
ATGACCTATAACCTCGAATTCGATGCGCGGGCTCTAAAGGAATGGCACAAATTAGGAGATACCGTGCGTCAGCAGCTCAA
GAAAAAGCTGGCTACGATTCTGGTTGCTCCGCGTGTTGAAGCCAATCGTCTGCATGCATTGCCTGACTGCTACAAAATCA
AACTGCGCAGTAGCGGCTATCGGCTGGTTTATCAGGTTATTGACCAAGAGGTTGTGGTCTTCGTGGTTGCGGTAGACAAG
CGTGAACGGGAAGAGGTTTATCGCAAGGCGACGGACCGGCTGGGTAGGTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8955.34 Da        Isoelectric Point: 4.6017

>AT21037 WP_002551444.1 NC_005773:186131-186370 [Pseudomonas savastanoi pv. phaseolicola 1448A]
MASINVRIDDDLKARAYLELEKLGVTPSELLRQTLQYVAERGQLPFKTVLMTEEDEALLATVRERLAAPQRVKVSLDDL

Download         Length: 240 bp

>AT21037 NC_005773:186131-186370 [Pseudomonas savastanoi pv. phaseolicola 1448A]
ATGGCGTCTATCAACGTTCGTATCGACGACGATCTCAAAGCGCGTGCTTACCTCGAGCTGGAAAAGCTTGGCGTCACCCC
CTCGGAGTTGCTGCGCCAAACCCTGCAGTACGTAGCTGAGCGTGGTCAGCTACCCTTCAAGACGGTTCTGATGACAGAGG
AAGACGAAGCGCTGTTGGCAACTGTGCGCGAGCGCCTTGCAGCTCCGCAGCGGGTCAAGGTTTCACTGGATGACCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2G4DBS4

Antitoxin

Source ID Structure
AlphaFold DB A0A0K8M1G9

References