21035

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 91662..92355 Replicon plasmid pND6-1
Accession NC_005244
Organism Pseudomonas putida ND6

Toxin (Protein)


Gene name tad Uniprot ID N2IHR9
Locus tag YSA_RS00550 Protein ID WP_003151133.1
Coordinates 91978..92355 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID N2IIN5
Locus tag YSA_RS00545 Protein ID WP_001172026.1
Coordinates 91662..91997 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
YSA_RS00510 87496..88419 - 924 WP_011117431.1 catechol 2,3-dioxygenase -
YSA_RS00515 88440..88757 - 318 WP_011117432.1 2Fe-2S iron-sulfur cluster binding domain-containing protein -
YSA_RS29960 88741..88959 - 219 WP_024265233.1 hypothetical protein -
YSA_RS00525 89257..90561 - 1305 WP_011154425.1 salicylate 1-monooxygenase -
YSA_RS00530 90605..90946 - 342 WP_025999701.1 hypothetical protein -
YSA_RS00535 90962..91288 - 327 WP_000091614.1 hypothetical protein -
YSA_RS00540 91312..91647 - 336 WP_000741275.1 hypothetical protein -
YSA_RS00545 91662..91997 - 336 WP_001172026.1 helix-turn-helix domain-containing protein Antitoxin
YSA_RS00550 91978..92355 - 378 WP_003151133.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
YSA_RS00555 92547..93149 + 603 WP_010465829.1 recombinase family protein -
YSA_RS00560 93133..96162 + 3030 WP_010799689.1 Tn3 family transposase -
YSA_RS00565 96348..97250 + 903 WP_011117383.1 HTH-type transcriptional activator NahR -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..101858 101858


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-113)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-43)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 18562.27 Da        Isoelectric Point: 5.5500

>T21035 WP_003151133.1 NC_005244:c92355-91978 [Pseudomonas putida ND6]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Download         Length: 378 bp

>T21035 NC_005244:c92355-91978 [Pseudomonas putida ND6]
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Antitoxin


Download         Length: 112 a.a.        Molecular weight: 16501.79 Da        Isoelectric Point: 5.5500

>AT21035 WP_001172026.1 NC_005244:c91997-91662 [Pseudomonas putida ND6]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Download         Length: 336 bp

>AT21035 NC_005244:c91997-91662 [Pseudomonas putida ND6]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
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Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A024ELN5

Antitoxin

Source ID Structure
AlphaFold DB A0A024EKI7

References