210269

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/GNAT-DUF1778
Location 2409280..2410025 Replicon chromosome
Accession NZ_CP079882
Organism Proteus terrae strain 20Q172tw

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag KZA80_RS11550 Protein ID WP_075673025.1
Coordinates 2409534..2410025 (+) Length 164 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag KZA80_RS11545 Protein ID WP_075673024.1
Coordinates 2409280..2409546 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KZA80_RS11510 (KZA80_11490) 2404941..2405423 + 483 WP_006533151.1 flagellar basal body-associated protein FliL -
KZA80_RS11515 (KZA80_11495) 2405429..2406460 + 1032 WP_023581831.1 flagellar motor switch protein FliM -
KZA80_RS11520 (KZA80_11500) 2406453..2406863 + 411 WP_006533153.1 flagellar motor switch protein FliN -
KZA80_RS11525 (KZA80_11505) 2406867..2407313 + 447 WP_075673022.1 flagellar biosynthetic protein FliO -
KZA80_RS11530 (KZA80_11510) 2407313..2408083 + 771 WP_023581828.1 flagellar type III secretion system pore protein FliP -
KZA80_RS11535 (KZA80_11515) 2408099..2408368 + 270 WP_069367481.1 flagellar biosynthesis protein FliQ -
KZA80_RS11540 (KZA80_11520) 2408374..2409156 + 783 WP_075673023.1 flagellar biosynthetic protein FliR -
KZA80_RS11545 (KZA80_11525) 2409280..2409546 + 267 WP_075673024.1 DUF1778 domain-containing protein Antitoxin
KZA80_RS11550 (KZA80_11530) 2409534..2410025 + 492 WP_075673025.1 GNAT family N-acetyltransferase Toxin
KZA80_RS11555 (KZA80_11535) 2410111..2411055 - 945 WP_087802138.1 flagellar hook-associated protein FlgL -
KZA80_RS11560 (KZA80_11540) 2411080..2412723 - 1644 WP_260797380.1 flagellar hook-associated protein FlgK -
KZA80_RS11565 (KZA80_11545) 2412842..2413828 - 987 WP_260797381.1 flagellar assembly peptidoglycan hydrolase FlgJ -
KZA80_RS11570 (KZA80_11550) 2413828..2414934 - 1107 WP_260797382.1 flagellar basal body P-ring protein FlgI -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(22-150)

Antitoxin

Vibrio phage ICP1, Orf50

(2-87)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 18228.15 Da        Isoelectric Point: 10.3194

>T210269 WP_075673025.1 NZ_CP079882:2409534-2410025 [Proteus terrae]
MGKVTAPEPLSNSHEVADFYSSENVLDNWIKQRGLKNQFLGASRTFVVCEKNKKRVVGYYSLATGSVNHTEAMSHIRRNM
PDPIPVIILARLAVDKTFHGKGLGADLLRDAVLRCHHVAENIGVRAIMVHALTENAKHFYLHHGFKASSTQDKILFLALK
KKI

Download         Length: 492 bp

>T210269 NZ_CP104484:206805-207290 [Salmonella enterica]
GTGGGACGTGTAACAGCACCAGAACCTTTGTCCGCTTTTCATCAGGTAGCTGAGTTCGTCAGCGGTGAAGCTGTGCTCGA
TGACTGGTTGAAGCAAAAGGGCCTCAAAAACCAGGCTCTCGGAGCGGCCAGAACATTTGTGGTGTGCAAGAAAGACACGA
AGCAAGTAGCCGGTTTTTACTCTCTGGCCACCGGTAGCGTCAACCATACAGAAGCGACAGGCAACCTTCGGCGTAACATG
CCAGATCCCATCCCTGTCATTATACTTGCCCGTCTTGCTGTCGATCTCTCATTCCATGGAAAAGGGCTTGGTGCTGATTT
ACTTCATGATGCAGTGCTTCGTTGCTATCGGGTTGCCGAGAATATTGGTGTACGTGCAATCATGGTTCATGCACTTACCG
AAGAAGCCAAAAATTTCTACATTCACCATGGTTTCAAATCATCACAAACTCAGCAGCGAACATTGTTCCTTAGGCTCCCT
CAATAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10111.62 Da        Isoelectric Point: 4.5256

>AT210269 WP_075673024.1 NZ_CP079882:2409280-2409546 [Proteus terrae]
MKADVQLNIRAKESQRALIDTAAEILHKSRTDFILETACQAAEDVILDRRTFNLNDAQYAEFIEIIDAPVDIDPALEKLL
MRKPLWEK

Download         Length: 267 bp

>AT210269 NZ_CP104484:206530-206817 [Salmonella enterica]
ATGCTATACAAGGGGTGTCTCATGAAATCAGATGTTCAACTTAACCTTAGAGCTAAGGAATCGCAGCGGGCGCTCATTGA
TGCAGCTGCGGAAATCCTTCACAAGTCACGTACAGATTTCATTCTGGAAACGGCCTGCCAGGCTGCCGAGAAAGTGATCC
TTGACCGCCGTGTATTTAACTTTAACGATGAGCAATATGAGGAGTTCATCAATCTGCTTGATGCACCGGTCGCAGATGAT
CCCGTTATCGAAAAACTGCTGGCAAGGAAACCTCAGTGGGACGTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References