Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PemK(toxin)
Location 5501095..5501675 Replicon chromosome
Accession NZ_CP079862
Organism Frankia sp. ArI3

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag KZA76_RS22680 Protein ID WP_044884113.1
Coordinates 5501331..5501675 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag KZA76_RS22675 Protein ID WP_044884114.1
Coordinates 5501095..5501337 (+) Length 81 a.a.

Genomic Context

KZA76_RS22660KZA76_RS22665KZA76_RS22670KZA76_RS22675KZA76_RS22680KZA76_RS22685
Location: 5496995..5498737 (1743 bp)
Type: Others
Protein ID: WP_055409723.1
Location: 5499086..5500111 (1026 bp)
Type: Others
Protein ID: WP_236706414.1
Location: 5500149..5501090 (942 bp)
Type: Others
Protein ID: WP_044884115.1
Location: 5501095..5501337 (243 bp)
Type: Antitoxin
Protein ID: WP_044884114.1
Location: 5501331..5501675 (345 bp)
Type: Toxin
Protein ID: WP_044884113.1
Location: 5501870..5503264 (1395 bp)
Type: Others
Protein ID: WP_044884112.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
KZA76_RS226605496995..5498737+1743WP_055409723.1aldehyde dehydrogenase family protein-
KZA76_RS226655499086..5500111+1026WP_236706414.1polyphosphate kinase 2-
KZA76_RS226705500149..5501090+942WP_044884115.1pyridoxal-phosphate dependent enzyme-
KZA76_RS226755501095..5501337+243WP_044884114.1ribbon-helix-helix domain-containing proteinAntitoxin
KZA76_RS226805501331..5501675+345WP_044884113.1type II toxin-antitoxin system PemK/MazF family toxinToxin
KZA76_RS226855501870..5503264-1395WP_044884112.1cyclopropane-fatty-acyl-phospholipid synthase family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(5-112)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 11874.80 Da        Isoelectric Point: 10.7849

>T210257 WP_044884113.1 NZ_CP079862:5501331-5501675 [Frankia sp. ArI3]
MVISRGDIRWVDLGEAEGSRPAKRRPVVVVQSAPYNASRLATAVAVVITSNTVLATMPGNIFLPAAVTGLPRDSVANVAA
IVTVNKDELGHAVGAVPGGLMRDLDRGLRHVLGL

Download         Length: 345 bp

>T210257 NZ_CP104482:322120-322488 [Salmonella enterica]
ATGACCCTACAACTTATCTCAGCGGAAGAGATAATTCAGTTTCACGACAGGCTTCTCCGCGTTACGCCTGGTGTAACAGG
CATGCCTGATCCTGGCCGCGCGGAAGCGCTAATGTATCGGGTACTCAATCAAATCGAATATGAAGGGGTGACCGACGTGT
GGCTGCTGGCGGCAATGCATTTGCTCACTATATCCCGTGGGTATATCTTCAATGATGGTAACAAACGCACCGCCTTATTT
ATTACGCTGCTGTTTTTAAAGCGTAACGGGATCTCACTCGCTGCGAATCCGGATTTTGTCGATATGACAGTCGATGCGGC
GGCAGGGCGGCTTACGCTGGAGCAAATTGCCGTTCGCTTACGTGCCTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8746.54 Da        Isoelectric Point: 4.1962

>AT210257 WP_044884114.1 NZ_CP079862:5501095-5501337 [Frankia sp. ArI3]
VKTAISIPDETFNEAERRAAALGVSRSEFFTTAARRYIEELDAQSLTERIDAALELAGPDDSFEAAARAGRRALGDSEDW

Download         Length: 243 bp

>AT210257 NZ_CP104482:321902-322123 [Salmonella enterica]
ATGCGTACGGTTAACTATAGCGAAGCGCGGCAAAATCTGGCCGAAGTCCTGGAAAGCGCGGTAACGGCGGGCCCTGTCAC
CATCACGCGTCGTGGGCATAAGTCCGCAGTGATCATCAGCGCCGAGGAGTTTGAGCGTTATCAGACGGCGCGAATGGATG
ATGAGTTTGCTGCCATTATGGCGGTTCATGGCAATGAGCTCAGGAAGCTGGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References