Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 5220477..5220991 Replicon chromosome
Accession NZ_CP079862
Organism Frankia sp. ArI3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KZA76_RS21485 Protein ID WP_044884753.1
Coordinates 5220731..5220991 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KZA76_RS21480 Protein ID WP_044884754.1
Coordinates 5220477..5220734 (+) Length 86 a.a.

Genomic Context

KZA76_RS21460KZA76_RS21465KZA76_RS32500KZA76_RS21470KZA76_RS21475KZA76_RS21480KZA76_RS21485KZA76_RS21510KZA76_RS21490KZA76_RS21495KZA76_RS21500
Location: 5215824..5216750 (927 bp)
Type: Others
Protein ID: WP_044884758.1
Location: 5216968..5217201 (234 bp)
Type: Others
Protein ID: WP_173667299.1
Location: 5217347..5217535 (189 bp)
Type: Others
Protein ID: Protein_4349
Location: 5217774..5217992 (219 bp)
Type: Others
Protein ID: WP_128423288.1
Location: 5218034..5220355 (2322 bp)
Type: Others
Protein ID: WP_044884755.1
Location: 5220477..5220734 (258 bp)
Type: Antitoxin
Protein ID: WP_044884754.1
Location: 5220731..5220991 (261 bp)
Type: Toxin
Protein ID: WP_044884753.1
Location: 5224717..5225316 (600 bp)
Type: Others
Protein ID: WP_011605735.1
Location: 5221514..5221996 (483 bp)
Type: Others
Protein ID: WP_236706000.1
Location: 5222237..5222893 (657 bp)
Type: Others
Protein ID: WP_009399358.1
Location: 5222890..5223969 (1080 bp)
Type: Others
Protein ID: WP_255648941.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
KZA76_RS214605215824..5216750+927WP_044884758.1M56 family metallopeptidase-
KZA76_RS214655216968..5217201+234WP_173667299.1hypothetical protein-
KZA76_RS325005217347..5217535+189Protein_4349hypothetical protein-
KZA76_RS214705217774..5217992+219WP_128423288.1dienelactone hydrolase family protein-
KZA76_RS214755218034..5220355+2322WP_044884755.1CoA transferase-
KZA76_RS214805220477..5220734+258WP_044884754.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
KZA76_RS214855220731..5220991+261WP_044884753.1Txe/YoeB family addiction module toxinToxin
KZA76_RS214905221514..5221996-483WP_236706000.1DUF6326 family protein-
KZA76_RS214955222237..5222893-657WP_009399358.1response regulator transcription factor-
KZA76_RS215005222890..5223969-1080WP_255648941.1sensor histidine kinase-
KZA76_RS215105224717..5225316+600WP_011605735.1response regulator-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(4-70)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10103.42 Da        Isoelectric Point: 8.0424

>T210255 WP_044884753.1 NZ_CP079862:5220731-5220991 [Frankia sp. ArI3]
VKLTWTDHAWDDYLYWQGQDRRTLKRINALIADIGRDPEGQGIGKPELLRNNLAGLRSRRIDDEHRLVYAVEPGQITIIA
CRYHYQ

Download         Length: 261 bp

>T210255 NZ_CP104479:c4719888-4719577 [Salmonella enterica]
ATGCAATTTATAGAAACGGAACTCTTTACTGAAGATGTTAAAAAACTGCTCGATGATGATGAATACCATAAGCTTCAGGT
TTTTATGGCTCAGCATCCAGATTGTGGTGATGTCATTCAGGAAACGGGCGGCCTGAGAAAAATGCGCTGGGGATCGCGAG
GCAAAGGAAAGCGTAGTGGCGTGCGAATTATCTATTTTCACCGTAGTCAACGGTATGAGATTCGCTTGCTTCTGATTTAT
CAAAAAGGCATTAAAGATGATCTCACGCCGCAGGAAAAAGCGGTGCTTCGTATGCTGAATGAGAGGTGGTAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9447.67 Da        Isoelectric Point: 4.7954

>AT210255 WP_044884754.1 NZ_CP079862:5220477-5220734 [Frankia sp. ArI3]
MVSAISASEARKTLFPLIEQVNTDHTPVEIVSKRGNAVLVSKEDWDAIVETNYLLRTPANARRLMESVEQWRTGGAVERP
VGPDE

Download         Length: 258 bp

>AT210255 NZ_CP104479:c4719576-4719286 [Salmonella enterica]
ATGGATAAAGTGTTATTTGAGCGATTAACTCAAAGTATGTCTCAAATGAATGAAATCATTGAAGGGACCCGTGAGCCTTC
TCGTACCTTTCATATTGATGCAATGAAGATTAAAGAAATACGGCAGGCATCTGGGTTGTCGCAATCTAAGTTTGCAGAAC
TGATTTCGGTCAACGTGGATACGCTGCGCAACTGGGAGCAAGGAAGACGTTCACCGACAGGGCCAGCCAAAGCGTTACTT
CGCGCCATTGCCAACGACCCGAGAAACGTTATACAAGCATTGCGTTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References