Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PHD(antitoxin)
Location 2371934..2372634 Replicon chromosome
Accession NZ_CP079862
Organism Frankia sp. ArI3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag KZA76_RS10020 Protein ID WP_044888587.1
Coordinates 2372209..2372634 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag KZA76_RS10015 Protein ID WP_044888595.1
Coordinates 2371934..2372212 (+) Length 93 a.a.

Genomic Context

KZA76_RS09985KZA76_RS09990KZA76_RS09995KZA76_RS10000KZA76_RS10005KZA76_RS10010KZA76_RS10015KZA76_RS10020KZA76_RS10030KZA76_RS10040KZA76_RS09980KZA76_RS10025KZA76_RS10035KZA76_RS10045
Location: 2367508..2367747 (240 bp)
Type: Others
Protein ID: WP_044888598.1
Location: 2367744..2368004 (261 bp)
Type: Others
Protein ID: WP_199865554.1
Location: 2368214..2369146 (933 bp)
Type: Others
Protein ID: WP_055871655.1
Location: 2369469..2369930 (462 bp)
Type: Others
Protein ID: WP_242419874.1
Location: 2369927..2370775 (849 bp)
Type: Others
Protein ID: WP_044888589.1
Location: 2370854..2371828 (975 bp)
Type: Others
Protein ID: WP_044888588.1
Location: 2371934..2372212 (279 bp)
Type: Antitoxin
Protein ID: WP_044888595.1
Location: 2372209..2372634 (426 bp)
Type: Toxin
Protein ID: WP_044888587.1
Location: 2373761..2374372 (612 bp)
Type: Others
Protein ID: WP_044888585.1
Location: 2375392..2376387 (996 bp)
Type: Others
Protein ID: WP_044888594.1
Location: 2367057..2367443 (387 bp)
Type: Others
Protein ID: WP_044888591.1
Location: 2372672..2373607 (936 bp)
Type: Others
Protein ID: WP_044888586.1
Location: 2374394..2375248 (855 bp)
Type: Others
Protein ID: WP_044888584.1
Location: 2376460..2377218 (759 bp)
Type: Others
Protein ID: WP_044888583.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
KZA76_RS099802367057..2367443-387WP_044888591.1hypothetical protein-
KZA76_RS099852367508..2367747+240WP_044888598.1type II toxin-antitoxin system Phd/YefM family antitoxin-
KZA76_RS099902367744..2368004+261WP_199865554.1PIN domain-containing protein-
KZA76_RS099952368214..2369146+933WP_055871655.1AraC family transcriptional regulator-
KZA76_RS100002369469..2369930+462WP_242419874.1cupin domain-containing protein-
KZA76_RS100052369927..2370775+849WP_044888589.1NmrA family NAD(P)-binding protein-
KZA76_RS100102370854..2371828+975WP_044888588.1alpha/beta hydrolase-
KZA76_RS100152371934..2372212+279WP_044888595.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
KZA76_RS100202372209..2372634+426WP_044888587.1type II toxin-antitoxin system VapC family toxinToxin
KZA76_RS100252372672..2373607-936WP_044888586.1SDR family oxidoreductase-
KZA76_RS100302373761..2374372+612WP_044888585.1TetR/AcrR family transcriptional regulator-
KZA76_RS100352374394..2375248-855WP_044888584.1helix-turn-helix transcriptional regulator-
KZA76_RS100402375392..2376387+996WP_044888594.1aldo/keto reductase-
KZA76_RS100452376460..2377218-759WP_044888583.1SDR family oxidoreductase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--2326481..237263446153


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(4-41)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15407.61 Da        Isoelectric Point: 5.6941

>T210254 WP_044888587.1 NZ_CP079862:2372209-2372634 [Frankia sp. ArI3]
VIYLDSAAVVKLVVAEPESPALVDWLNVRDALPRFTSTLAEVEVTRAIRRAAPEALGRVPRVLDRMYRLEIDAHVRAVAA
AFDDPLLRSPDAIHLATALRLSDENDTRMEAFVTYDKRLLEAARRADLPTAAPGPHSAAGS

Download         Length: 426 bp

>T210254 NZ_CP104479:c4409977-4409486 [Salmonella enterica]
ATGATCTCCTCCCCTGAGCCGCTTCATGCCGGACATATTCTTACTCCGTTTTGCTGCGGTGTGGATTCTATGGATAACTG
GCTGAAACAGCGGGCGATGAAAAATCAGACCACTGGTGCGTCCCGTACCTTTGTGTGTTGTGGCAGCGATTCGAACGTAC
TGGCCTATTACTCGCTGGCGTCCAGCGCGGTCACGACGAATACCGCCCCCGGTCGCTTTCGTCGCAATATGCCTGACCCG
ATCCCGATTGTGGTATTGGGGCGTCTGGCGGTGGATAAATCGCTTCATGGGCAGGGCGTTGGTCGGGCGCTGGTACGCGA
CGCAGGGCTGCGGGTTATTCAGGTGGCGGAGACTATCGGCATTCGCGGGATGCTGGTTCACGCCCTGTCGGATGAAGCGC
GGGAATTTTACCAGCGGGTGGGGTTTGAACCATCGCCGATGGATCCGATGATGTTGATGGTGACGTTGGGGGATTTGGTG
GAGAGTGTTTAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10007.39 Da        Isoelectric Point: 5.1351

>AT210254 WP_044888595.1 NZ_CP079862:2371934-2372212 [Frankia sp. ArI3]
VDRVGVRELNQSTSQVIDRVRRGETIEVTDRGRPVARLVPIGRGTAALDRLVTEGRAIPPATEGPVPMPPLLGDPAVSAT
NDLIAMRDEERW

Download         Length: 279 bp

>AT210254 NZ_CP104479:c4410267-4409974 [Salmonella enterica]
ATGCCAGCCGCAAACAGTATGGCGATGAAACGCGAAACCCTGAACCTGCGCATCAAGCCCGCCGAGCGCGATCTTATCGA
TCGGGCGGCGAAAGCCAGAGGGAAAAACCGCACAGACTTTGTGCTGGAAGCTGCCCGCGCTGCCGCAGAGGAAGCGCTGA
TCGAACAACGCATCATTATGGCCGATCCAGAGGCTTATCAGGAATTTCTCGCTCGTTTGGATCAAACACCTTCACCTAAT
GCCGCACTGCGTAAAACCATGCAGACCCCTGCACCGTGGGAGCAGGAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
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References