Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1220983..1221511 Replicon chromosome
Accession NZ_CP079860
Organism Vibrio neptunius strain KCTC 12702

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KW548_RS22280 Protein ID WP_206372260.1
Coordinates 1220983..1221273 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KW548_RS22285 Protein ID WP_206372259.1
Coordinates 1221263..1221511 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KW548_RS22255 (KW548_22260) 1216883..1217320 - 438 WP_219348743.1 BspA family leucine-rich repeat surface protein -
KW548_RS22260 (KW548_22265) 1217903..1218553 + 651 WP_219348744.1 hypothetical protein -
KW548_RS22265 (KW548_22270) 1219511..1219762 + 252 WP_045974129.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
KW548_RS22270 (KW548_22275) 1219752..1220039 + 288 WP_045974128.1 type II toxin-antitoxin system RelE/ParE family toxin -
KW548_RS22275 (KW548_22280) 1220359..1220640 - 282 WP_257713423.1 hypothetical protein -
KW548_RS22280 (KW548_22285) 1220983..1221273 - 291 WP_206372260.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KW548_RS22285 (KW548_22290) 1221263..1221511 - 249 WP_206372259.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
KW548_RS22290 (KW548_22295) 1221594..1221741 - 148 Protein_1159 IS110 family transposase -
KW548_RS22295 (KW548_22300) 1221786..1222049 + 264 WP_219348745.1 hypothetical protein -
KW548_RS22300 (KW548_22305) 1222092..1222775 + 684 WP_219348746.1 SDR family oxidoreductase -
KW548_RS22305 (KW548_22310) 1222841..1223254 + 414 WP_219348747.1 GFA family protein -
KW548_RS22310 (KW548_22315) 1223393..1223950 + 558 WP_219348748.1 nucleotidyltransferase family protein -
KW548_RS22315 (KW548_22320) 1223989..1224627 + 639 WP_219348749.1 HAD hydrolase-like protein -
KW548_RS22320 (KW548_22325) 1224865..1225122 + 258 WP_045974123.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
KW548_RS22325 (KW548_22330) 1225110..1225424 + 315 WP_219348750.1 type II toxin-antitoxin system RelE/ParE family toxin -
KW548_RS22330 (KW548_22335) 1225646..1226128 + 483 WP_257713424.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1207957..1223254 15297


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(12-75)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11276.27 Da        Isoelectric Point: 10.6832

>T210251 WP_206372260.1 NZ_CP079860:c1221273-1220983 [Vibrio neptunius]
MTYKLDFKKSALKEWKKLGSTLQQQFKKKLIERLDNPHVPASKLSGSDNMYKIKLRQSGYRLVYKVEDDVIIVTVLAVGK
RERSNVYRKAMKRLDD

Download         Length: 291 bp

>T210251 NZ_CP104479:3763541-3763816 [Salmonella enterica]
ATGAATGCCTCCGGCGTCAGCGTCCGCCACATCAACAGCGAAACCTGTATAACCACCTGTTACTCACAAATCCCCAGCCT
GCACCTTAAGGGTGACTGGCAGGAAGAAGCGGGATTTGAGACCGGGCGCAGCGTGACCGTGAAGATCTCCGAGGGATGTT
TGATCCTGATGGCTGAGACGGACGAAGTGAGGGAGCTACGGAAGGAGCTTTATCAGGTGAAAAAGTCGATGAAGCATATT
AAGGCGGGGGTAAATGATGTGGTGAACGGGAATTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9079.37 Da        Isoelectric Point: 3.9610

>AT210251 WP_206372259.1 NZ_CP079860:c1221511-1221263 [Vibrio neptunius]
MTTRILADVAASITELKANPMKVATSAYGEPVAVLNRNEPAFYCVPAEAYEMMMDRLEDLELLALAKERESEESISVNID
DL

Download         Length: 249 bp

>AT210251 NZ_CP104479:c3763806-3763384 [Salmonella enterica]
TTCACCACATCATTTACCCCCGCCTTAATATGCTTCATCGACTTTTTCACCTGATAAAGCTCCTTCCGTAGCTCCCTCAC
TTCGTCCGTCTCAGCCATCAGGATCAAACATCCCTCGGAGATCTTCACGGTCACGCTGCGCCCGGTCTCAAATCCCGCTT
CTTCCTGCCAGTCACCCTTAAGGTGCAGGCTGGGGATTTGTGAGTAACAGGTGGTTATACAGGTTTCGCTGTTGATGTGG
CGGACGCTGACGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTCTCCGCCGGATACTGGCTGATTGTGGA
GCTCAGGGTGAGTGAGTATGGGCGCGACATCCTGGCACTGTGCCCCCCTCTCCCCGGCCAGCACCGGGCGGTGATGAGCA
ACCGGCTGCCGGGGCCGTATTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References