Detailed information of TA system TA210250

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 1219511..1220039
• Replicon: chromosome
• Accession: NZ_CP079860
• Organism: Vibrio neptunius strain KCTC 12702

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: KW548_RS22270
• Protein ID: WP_045974128.1
• Coordinates: 1219752..1220039 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: KW548_RS22265
• Protein ID: WP_045974129.1
• Coordinates: 1219511..1219762 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KW548_RS22245 (KW548_22250)	1214800..1215483	+	684	WP_206374008.1	HAD family hydrolase	-
KW548_RS22250 (KW548_22255)	1215729..1216844	-	1116	WP_219348742.1	BspA family leucine-rich repeat surface protein	-
KW548_RS22255 (KW548_22260)	1216883..1217320	-	438	WP_219348743.1	BspA family leucine-rich repeat surface protein	-
KW548_RS22260 (KW548_22265)	1217903..1218553	+	651	WP_219348744.1	hypothetical protein	-
KW548_RS22265 (KW548_22270)	1219511..1219762	+	252	WP_045974129.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
KW548_RS22270 (KW548_22275)	1219752..1220039	+	288	WP_045974128.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
KW548_RS22275 (KW548_22280)	1220359..1220640	-	282	WP_257713423.1	hypothetical protein	-
KW548_RS22280 (KW548_22285)	1220983..1221273	-	291	WP_206372260.1	type II toxin-antitoxin system RelE/ParE family toxin	-
KW548_RS22285 (KW548_22290)	1221263..1221511	-	249	WP_206372259.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
KW548_RS22290 (KW548_22295)	1221594..1221741	-	148	Protein_1159	IS110 family transposase	-
KW548_RS22295 (KW548_22300)	1221786..1222049	+	264	WP_219348745.1	hypothetical protein	-
KW548_RS22300 (KW548_22305)	1222092..1222775	+	684	WP_219348746.1	SDR family oxidoreductase	-
KW548_RS22305 (KW548_22310)	1222841..1223254	+	414	WP_219348747.1	GFA family protein	-
KW548_RS22310 (KW548_22315)	1223393..1223950	+	558	WP_219348748.1	nucleotidyltransferase family protein	-
KW548_RS22315 (KW548_22320)	1223989..1224627	+	639	WP_219348749.1	HAD hydrolase-like protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1207957..1223254	15297

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (11-70)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11002.00 Da
• Isoelectric Point: 10.5506

>T210250 WP_045974128.1 NZ_CP079860:1219752-1220039 [Vibrio neptunius]
MTYKLKFLPAAKKEWSKLAPPIQSQFKKKLKERLENPHVPASKLRGYDSVYKIKLRTAGYRLAYEVIDDEIVVYVLAIGK
RDKDAVYKKLATRSS

Nucleotide

• Length: 288 bp

>T210250 NZ_CP104479:3574153-3574371 [Salmonella enterica]
ATGTCTGATAAACCATTAACTAAAACTGATTATTTGATGCGTTTACGGCGCTGTCAGACAATTGACACTCTGGAGCGCGT
CATTGAGAAAAATAAATATGAATTGTCCGACAATGAGCTGGCTGTATTTTACTCAGCTGCGGATCACCGTCTTGCAGAAT
TGACGATGAACAAACTCTACGACAAGATCCCCTCTTCAGTATGGAAATTCATTCGTTAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9214.40 Da
• Isoelectric Point: 4.0414

>AT210250 WP_045974129.1 NZ_CP079860:1219511-1219762 [Vibrio neptunius]
MRQVLADYSASISELKKNPTALLNEADGSAIAILNHNKPAAYLVPAETYEFLMDMLDDYELAKLVESRRGELSEAVEVNI
DDL

Nucleotide

• Length: 252 bp

>AT210250 NZ_CP104479:3573751-3574125 [Salmonella enterica]
ATGGACGAATACTCACCCAAAAGACATGATATAGCACAGCTTAAATTTCTTTGCGAAACCCTGTATCATGACTGTCTTGC
AAACCTTGAAGAAAGCAACCATGGCTGGGTTAATGACCCGACCTCAGCAGTCAACCTGCAGCTCAATGAGCTGATAGAGC
ATATTGCAACTTTCGCGCTTAATTATAAAATTAAGTACAATGAAGACAATAAATTGATTGCGCAGATAGATGAATACCTG
GACGACACCTTTATGTTGTTCAGCAGCTATGGTATTAATACGCAGGATTTGCAAAAATGGCGTAAATCGGGCAACCGCCT
GTTCCGTTGTTTCGTCAACGCCACCAGGGCTAATCCTGTTAGTTTGTCTTGTTAA