Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 391799..392459 Replicon chromosome
Accession NZ_CP079839
Organism Salmonella enterica strain LHICA_E3

Toxin (Protein)


Gene name cptA Uniprot ID A0A701Y5L0
Locus tag JMJ87_RS01900 Protein ID WP_000244758.1
Coordinates 391799..392212 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag JMJ87_RS01905 Protein ID WP_000351186.1
Coordinates 392193..392459 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMJ87_RS01880 (387740) 387740..389473 - 1734 WP_000813384.1 single-stranded-DNA-specific exonuclease RecJ -
JMJ87_RS01885 (389479) 389479..390192 - 714 WP_079797899.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
JMJ87_RS01890 (390216) 390216..391112 - 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
JMJ87_RS01895 (391225) 391225..391746 + 522 WP_058114568.1 flavodoxin FldB -
JMJ87_RS01900 (391799) 391799..392212 - 414 WP_000244758.1 protein YgfX Toxin
JMJ87_RS01905 (392193) 392193..392459 - 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
JMJ87_RS01910 (392709) 392709..393689 + 981 WP_000874162.1 tRNA-modifying protein YgfZ -
JMJ87_RS01915 (393797) 393797..394456 - 660 WP_023180797.1 hemolysin III family protein -
JMJ87_RS01920 (394620) 394620..394931 - 312 WP_001182973.1 N(4)-acetylcytidine aminohydrolase -
JMJ87_RS01925 (395089) 395089..396522 + 1434 WP_079974061.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16249.21 Da        Isoelectric Point: 10.7538

>T210225 WP_000244758.1 NZ_CP079839:c392212-391799 [Salmonella enterica]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMLLLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLHPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRIVLQQPISRQH

Download         Length: 414 bp

>T210225 NZ_CP104473:c45264-45115 [Escherichia coli]
ATGACGAAATATACCCTAATTGGGTTGCTCGCTGTGTGCGCCACGGTGTTGTGTTTTTCACTGATATTCAGGGAACGGTT
ATGTGAGCTGAATATTCACAGGGGAAATACAGTGGTGCAGGTAACTCTGGCCTACGAAGCACGGAAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT210225 WP_000351186.1 NZ_CP079839:c392459-392193 [Salmonella enterica]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT210225 NZ_CP104473:45308-45369 [Escherichia coli]
TTGAGATACTTCATGCAGGCCTCACGAGTTAATGGATTAACAAGTGGGGTCTTCGCATTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A701Y5L0

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References