Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4332332..4332848 Replicon chromosome
Accession NZ_CP079838
Organism Salmonella enterica subsp. salamae strain LHICA_SA3

Toxin (Protein)


Gene name relE Uniprot ID V1HEI0
Locus tag JMJ83_RS20795 Protein ID WP_000220584.1
Coordinates 4332332..4332616 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JMJ83_RS20800 Protein ID WP_079797067.1
Coordinates 4332606..4332848 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMJ83_RS20780 (4327552) 4327552..4329204 + 1653 WP_079974597.1 alpha,alpha-phosphotrehalase -
JMJ83_RS20785 (4329613) 4329613..4331751 + 2139 WP_053507663.1 anaerobic ribonucleoside-triphosphate reductase -
JMJ83_RS20790 (4331858) 4331858..4332322 + 465 WP_046094240.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
JMJ83_RS20795 (4332332) 4332332..4332616 - 285 WP_000220584.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JMJ83_RS20800 (4332606) 4332606..4332848 - 243 WP_079797067.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
JMJ83_RS20805 (4332927) 4332927..4334840 - 1914 WP_141125049.1 BglG family transcription antiterminator -
JMJ83_RS20810 (4334857) 4334857..4335597 - 741 WP_079974599.1 KDGP aldolase family protein -
JMJ83_RS20815 (4335594) 4335594..4336712 - 1119 WP_001139196.1 DgaE family pyridoxal phosphate-dependent ammonia lyase -
JMJ83_RS20820 (4336696) 4336696..4337829 - 1134 WP_000459961.1 amidohydrolase/deacetylase family metallohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-65)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11085.02 Da        Isoelectric Point: 10.3015

>T210223 WP_000220584.1 NZ_CP079838:c4332616-4332332 [Salmonella enterica subsp. salamae]
MTYELEFDPRALKEWQKLGETVKKQFRKKLVDVLSNPRVESARLRELPDCYKIKLKTSGYRLVYQVQDDVVLVVVIAIGK
REKSAVYRQADKRL

Download         Length: 285 bp

>T210223 NZ_CP104472:c4974928-4974821 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9041.44 Da        Isoelectric Point: 5.0651

>AT210223 WP_079797067.1 NZ_CP079838:c4332848-4332606 [Salmonella enterica subsp. salamae]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAENGRMPVKTVTISDSEDVLLQTVRERLANPQKGIRVSLDDL

Download         Length: 243 bp

>AT210223 NZ_CP104472:4974976-4975042 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTAAACCTCTCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A741MVA9

Antitoxin

Source ID Structure

References