Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Doc-RelB
Location 2296873..2297477 Replicon chromosome
Accession NZ_CP079837
Organism Salmonella enterica subsp. salamae strain LHICA_SA2

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag JMJ84_RS10860 Protein ID WP_134947603.1
Coordinates 2296873..2297259 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag JMJ84_RS10865 Protein ID WP_079789171.1
Coordinates 2297256..2297477 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMJ84_RS10845 (2292965) 2292965..2294167 - 1203 WP_079808072.1 MalY/PatB family protein -
JMJ84_RS10850 (2294180) 2294180..2295631 - 1452 WP_001276629.1 Na+/H+ antiporter NhaC -
JMJ84_RS10855 (2295775) 2295775..2296782 - 1008 WP_219142279.1 LacI family DNA-binding transcriptional regulator -
JMJ84_RS10860 (2296873) 2296873..2297259 - 387 WP_134947603.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
JMJ84_RS10865 (2297256) 2297256..2297477 - 222 WP_079789171.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
JMJ84_RS10870 (2298016) 2298016..2299095 - 1080 WP_219142281.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
JMJ84_RS10875 (2299287) 2299287..2299775 - 489 WP_079808077.1 MarR family transcriptional regulator -
JMJ84_RS10880 (2299820) 2299820..2301337 + 1518 WP_219142283.1 FAD-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Death on curing protein

(2-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-53)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14553.42 Da        Isoelectric Point: 5.9754

>T210200 WP_134947603.1 NZ_CP079837:c2297259-2296873 [Salmonella enterica subsp. salamae]
MIWVSAQEVIALHDRILQRFPGVAGLSDPGRAQALIYRVQNRVHYEDVTDLFELAATYWVAIARGHIFHDGNKRTAFFVT
MTFLWRNGIRIHDTDNTLEDLTVEAATGEKTVDQLAQRLRELVDSSGN

Download         Length: 387 bp

>T210200 NZ_CP104471:c3757181-3756771 [Enterobacter hormaechei]
GTGGTCCTGTGGCAATCTGATCTTCGCGTCTCGTGGCGCTCACAGTGGATGTCCTTACTGCTCCACGGTCTGGTCGCGGC
AATGGTGTTATTGGTGCCGTGGCCGCTAAGCTATACCCCTCTGTGGCTGCTTTTGCTGTCGTTTGTGGTGTTTGATAGCG
TGCGCAGCCAGCGTCGAATCAACGCCCGTCAGGGTGAAATTAAGCTGCTGATGGATTCTCGCCTGCGCTGGCAGGGAAAA
GAGTGGGAAATGATAGGGACGCCGTGGATGCTCAACACCGGGATGATGCTACGGCTGCGTCGGGTCGAGGATAACCGTCG
CCAGCACCTGTGGCTGGCCGCAGACAGTATGGATCCCGCGGAGTGGCGGGATCTGCGCCGGCTAATCGTGCAACAGCCAA
CGCAGGAATAA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8206.21 Da        Isoelectric Point: 5.6492

>AT210200 WP_079789171.1 NZ_CP079837:c2297477-2297256 [Salmonella enterica subsp. salamae]
MQTYTSTQARANIATVLDTALNGEPVEITRRDGRAAVLISKAEFEAYQNAKLDAEFDVIMQRHEHTIKALTDR

Download         Length: 222 bp

>AT210200 NZ_CP104471:c3757428-3757162 [Enterobacter hormaechei]
ATGGATATTAACAACAAGGCCCGTATTCACTGGGCGTGCCGTCGCGGCATGCGTGAACTTGATATCTCCATCATGCCTTT
CTTCGAGTATGAGTACGACAGCTTAAGCGATGACGATAAGCGCCTGTTTGTCCGTCTGCTTGAGTCTGACGATCCGGATT
TATTCAACTGGCTGATGAATCACGGCAAGCCCGCCGACACCGAGTTGCAACGGATGGTGCAATTAATTCAAACACGGAAT
CAGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References