Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PsyrTA/-
Location 3847882..3850460 Replicon chromosome
Accession NZ_CP079823
Organism Aeromonas veronii strain HD6454

Toxin (Protein)


Gene name PsyrT Uniprot ID -
Locus tag KW556_RS17930 Protein ID WP_259583947.1
Coordinates 3849261..3850460 (-) Length 400 a.a.

Antitoxin (Protein)


Gene name PsyrA Uniprot ID -
Locus tag KW556_RS17925 Protein ID WP_259583946.1
Coordinates 3847882..3849264 (-) Length 461 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KW556_RS17905 (KW556_17840) 3843424..3844254 + 831 WP_232048272.1 hypothetical protein -
KW556_RS17910 (KW556_17845) 3844708..3846269 + 1562 WP_088813959.1 IS3-like element ISAs20 family transposase -
KW556_RS17915 (KW556_17850) 3846417..3846965 + 549 WP_011899358.1 hypothetical protein -
KW556_RS17920 (KW556_17855) 3846983..3847708 - 726 WP_011899359.1 hypothetical protein -
KW556_RS17925 (KW556_17860) 3847882..3849264 - 1383 WP_259583946.1 DNA-processing protein DprA Antitoxin
KW556_RS17930 3849261..3850460 - 1200 WP_259583947.1 helicase-related protein Toxin
KW556_RS17935 3850528..3851379 - 852 WP_259583948.1 DEAD/DEAH box helicase -
KW556_RS17940 (KW556_17870) 3851394..3851618 - 225 WP_259583949.1 hypothetical protein -
KW556_RS17945 (KW556_17875) 3851798..3853216 + 1419 WP_004576012.1 IS66-like element ISAs21 family transposase -
KW556_RS17950 (KW556_17880) 3853199..3854083 - 885 WP_259583950.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island sul1 / aadA16 / catB3 / blaOXA-21 / aac(6')-IIa / aph(3'')-Ib / aph(6)-Id / aac(6')-Ib-cr / qnrVC6 / mph(A) / dfrA27 vgrG2 / vgrG / hcp 3782911..3919363 136452


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Phosphoribosyltransferase domain

(269-382)

Antitoxin

DNA recombination-mediator protein A

(93-293)


Sequences

Toxin        


Download         Length: 400 a.a.        Molecular weight: 43893.85 Da        Isoelectric Point: 6.5989

>T210161 WP_259583947.1 NZ_CP079823:c3850460-3849261 [Aeromonas veronii]
VATTALGMGYDKPDLSFVIHYQAPGSIVAYYQQVGRAGRGIDHAVGVLMSGVEDQDIHEFFRESAFPSEAHVHEILQVLE
EADGLSLRGIEEQTNLRHGQIEKVLKLLSVDNPAPVIKDGNQWRRTAVPYQMDHARIAHLTGQRVQEWQEVQAYLTDTSC
KMTFLRRALDDLDPAPCGKCSSCLGHPVINVPVDPGLAHRAGTFLKHAEMVIEPKAQVAAKAFVQYGFRGNLPQNLRAQE
GRVLSRWGDAGWGRTVADNKHAGHFSDELVEAMVAMIQERWLPDPAPQWVCCVPSRNHPALVPDFARRLAARLGLPFIDA
VHKVRDNQPQKGQQNRFHQCQNLDGAFAINQPLPNTPVLLVDDIVDSGWTLTVIAALLQQAGSGAVYPVALASSSVKDS

Download         Length: 1200 bp

>T210161 NZ_CP104442:c3607286-3606951 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCTGG
ACATCGTCCAGCTGTTGTCCTGAGTCCTTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG

Antitoxin


Download         Length: 461 a.a.        Molecular weight: 50574.37 Da        Isoelectric Point: 5.0620

>AT210161 WP_259583946.1 NZ_CP079823:c3849264-3847882 [Aeromonas veronii]
MNVSSPLSATAQATLLLTSYFSKTSSEDAKPLTNAEWGRFALWLKEKSNTPADLLVTDPKALLHGWYDARISVDRIVQLL
NRGHSLAIAMEKWQRAGLWVVTRSDPEYPWRLKQRLKTDSPPVLFGCGNRALLNAGGLAVIGSRNANDEDLMFTNEVGAK
AALERIAIVSGGARGVDETAMLGAMKQDGVVIGVMADSLLKAATSSKWRKGLMDGHAVLVSPFYPEAGFSAGNAMARNKY
IYCLADTSLVIHSGKKGGTLNGAEENLKKFWVPLWVKHTTDKDAANADLVAKGGRWLEADAQTLTIADLMRIEGGRANQV
KEEQVDLFSSMPTQPELFAESKFTLETETETETETETETETEAETEPNPKVAIIEETVVKTTPSETIVEINDHLSSSVDF
YQLFITELQRLASNPIAIDDLIGLTGLHRLQLNDWLKQAENDGVVKKLNRPVRYQVQEKS

Download         Length: 1383 bp

>AT210161 NZ_CP104442:c3607534-3607286 [Escherichia coli]
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References