Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2045339..2045483 Replicon chromosome
Accession NZ_CP079802
Organism Klebsiella variicola strain EMBL-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2045375..2045477 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2045339..2045483 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KU883_RS09870 (KU883_09865) 2040469..2042529 + 2061 WP_012541258.1 oligopeptidase B -
KU883_RS09875 (KU883_09870) 2042533..2043192 - 660 WP_012541259.1 exodeoxyribonuclease X -
KU883_RS09880 (KU883_09875) 2043271..2043501 - 231 WP_012541260.1 DNA polymerase III subunit theta -
KU883_RS09885 (KU883_09880) 2043615..2043989 + 375 WP_012541261.1 CopC domain-containing protein YobA -
KU883_RS09890 (KU883_09885) 2043993..2044862 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
KU883_RS09895 (KU883_09890) 2044879..2045217 + 339 WP_008804271.1 YebY family protein -
- 2045339..2045483 - 145 - - Antitoxin
- 2045375..2045477 + 103 - - Toxin
KU883_RS09900 (KU883_09895) 2045862..2046005 - 144 WP_046621074.1 Ecr family regulatory small membrane protein -
KU883_RS09905 (KU883_09900) 2046109..2047098 - 990 WP_032691211.1 VirK/YbjX family protein -
KU883_RS09910 (KU883_09905) 2047234..2047887 + 654 WP_022066249.1 protein-serine/threonine phosphatase -
KU883_RS09915 (KU883_09910) 2047884..2048075 - 192 WP_002911395.1 YebW family protein -
KU883_RS09920 (KU883_09915) 2048173..2048412 - 240 WP_002911393.1 YebV family protein -
KU883_RS09925 (KU883_09920) 2048528..2049961 - 1434 WP_077139314.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T210120 NZ_CP079802:2045375-2045477 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT210120 NZ_CP079802:c2045483-2045339 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References