Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 65..578 Replicon plasmid pAJ_082-5
Accession NZ_CP079796
Organism Acinetobacter johnsonii strain AJ_082

Toxin (Protein)


Gene name yoeB Uniprot ID N8YGB2
Locus tag EGT72_RS18190 Protein ID WP_000184943.1
Coordinates 65..328 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID N8ZW56
Locus tag EGT72_RS18195 Protein ID WP_000557944.1
Coordinates 315..578 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EGT72_RS18190 (EGT72_018190) 65..328 - 264 WP_000184943.1 Txe/YoeB family addiction module toxin Toxin
EGT72_RS18195 (EGT72_018195) 315..578 - 264 WP_000557944.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
EGT72_RS18200 (EGT72_018200) 932..2014 + 1083 WP_006582650.1 zinc-dependent alcohol dehydrogenase family protein -
EGT72_RS18205 (EGT72_018205) 2500..3030 - 531 WP_071852199.1 plasmid replication DNA-binding protein -
EGT72_RS18210 (EGT72_018210) 3109..4020 - 912 WP_004733876.1 replication initiation protein RepM -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..6837 6837


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10649.09 Da        Isoelectric Point: 8.4866

>T210113 WP_000184943.1 NZ_CP079796:c328-65 [Acinetobacter johnsonii]
MTNRNVEWTDNAWDEYIYWQTQDKKILKRINTLIKECQRTPFEGTGKPEPLKANLSGFWSRRIDEKHRLVYEVTDERISI
IQCRFHY

Download         Length: 264 bp

>T210113 NZ_CP104403:c1212304-1211993 [Enterobacter hormaechei subsp. steigerwaltii]
ATGCACATAGTCTCAAGAGCGCCTTTCGACACAGCGGCCAGACATTATCCCAATCAAGCACAAGCCCTGGACGATCTTTA
CCGGGTACTAAAAAAGGAACACTACCCCTCACCAGACGAGATGCGAAAGCGCTTTCCTAGCCTGGACCGGATGAAATACC
GGGAAAAATGGTGGGTCATTGATGTGGGTGGCGGGCATCTAAGAGTGATGTTTTTTGCTGATTTTGAGCGTGGAAAGATC
TTCATCAAACACATCAGCACTCACGCAGACTATGACAAGCTCACGGACTACTACCGGAGAACGAAAGAATGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9834.99 Da        Isoelectric Point: 5.0829

>AT210113 WP_000557944.1 NZ_CP079796:c578-315 [Acinetobacter johnsonii]
MHVFTYTDARNNLKSVLDKVIDDVDVAFITRKEGGHAVVMGQDHYDSLMETLYLLSSPNNASRLNESIAQLRAGKTKHRE
LIEDDES

Download         Length: 264 bp

>AT210113 NZ_CP104403:c1211996-1211577 [Enterobacter hormaechei subsp. steigerwaltii]
ATGAATTATGCAGCAGCCATCAAAGCGGCAAACGCTCTGACAAACGAGCTCCCTTTCCTGGGTTCAAGCCCGTCGCGGCA
AGACTACGAGGATGCGCTGGCGCTGGTGGAGTATCTTATCGAGCACGACCCCGATAACCCGCTGGTAGATATGCTCACTG
CCAAAATCGATAAGTATGAAAACGCGTCCCCGGAGTTTGCAGAATTTAACGCGCGTATTGCCAGCATTCCGTCAGGCGTT
GCGTTACTGCGAACGCTAATGGATCAGTACCAGCTCACTCAGAGTGATTTCGAGAACGAGATTGGTAAGAAGTCTCTGGT
AAGTCGGATCCTTAACGGACAGCGCACGTTAACGCTAGATCATATGCGAGCGCTGGCGAAGCGTTTCGGTTTGCCGGTGA
GCGCATTTGTGGGGAACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6C0XPS2

Antitoxin

Source ID Structure
AlphaFold DB A0A6C0XPU2

References