Detailed information of TA system TA210107

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/Cpta(toxin)
• Location: 2751734..2752383
• Replicon: chromosome
• Accession: NZ_CP079792
• Organism: Acinetobacter johnsonii strain AJ_082

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: EGT72_RS13620
• Protein ID: WP_114836536.1
• Coordinates: 2751734..2752120 (-)
• Length: 129 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: N9CU98
• Locus tag: EGT72_RS13625
• Protein ID: WP_004977895.1
• Coordinates: 2752126..2752383 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EGT72_RS13605 (EGT72_013605)	2747067..2749349	-	2283	WP_125280248.1	TRAP transporter large permease subunit	-
EGT72_RS13610 (EGT72_013610)	2749532..2750104	-	573	WP_125280249.1	rhombosortase	-
EGT72_RS13615 (EGT72_013615)	2750176..2751213	-	1038	WP_125280250.1	hypothetical protein	-
EGT72_RS13620 (EGT72_013620)	2751734..2752120	-	387	WP_114836536.1	hypothetical protein	Toxin
EGT72_RS13625 (EGT72_013625)	2752126..2752383	-	258	WP_004977895.1	succinate dehydrogenase assembly factor 2	Antitoxin
EGT72_RS13630 (EGT72_013630)	2752576..2753748	+	1173	WP_125280252.1	acyl-CoA dehydrogenase family protein	-
EGT72_RS13635 (EGT72_013635)	2753784..2754467	-	684	WP_228740193.1	alpha/beta hydrolase	-
EGT72_RS13640 (EGT72_013640)	2754707..2756197	-	1491	WP_125280253.1	NAD(P)/FAD-dependent oxidoreductase	-
EGT72_RS13645 (EGT72_013645)	2756393..2756758	-	366	WP_004691290.1	50S ribosomal protein L17	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (5-127)

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 129 a.a.
• Molecular weight: 15282.29 Da
• Isoelectric Point: 10.4419

>T210107 WP_114836536.1 NZ_CP079792:c2752120-2751734 [Acinetobacter johnsonii]
MEHRHFQLKPSRLAYVFQLSIYAVLMLVLYQLLPLGLWLIALVAGFVLYLFFLRGPQHLQLQHLDGRDWSLSLQKQTNVQ
RVQISHIVDHRAYIVIYFQHFRAKPMLVWCDQLPITQWKALKILTKMQ

Nucleotide

• Length: 387 bp

>T210107 NZ_CP104403:31722-32036 [Enterobacter hormaechei subsp. steigerwaltii]
ATGCATTTAATCTCAATGAAGGCAATTTTGGATGCGGTAAGCCAGTTCCCGCAACACAGAGAAGAGCTTCTCTTTTTAGG
ACGAGTTATTGAAAAGAGCCACTGCCCGACGCCCGCTGCACTGAGAAAACTTTTCCCAACGCTGGATAACTTCAAGTATC
TTGATAAGCATTATGTTATTGATATTGCAAATAACAATCTCAGAGTAGTGGCTCTCATATTCTTTGAAAGCCAAAAGTTT
TATGTGCGCCATGTTTTTACTCATAAGGAATATGACCGTTTTACGGAGAAACATCGCACTAAGGGGAAGAAATGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10181.71 Da
• Isoelectric Point: 4.7119

>AT210107 WP_004977895.1 NZ_CP079792:c2752383-2752126 [Acinetobacter johnsonii]
MTEEMSLEERKVIYRARRGLKEIDVYFDPYVKNYYLQADPAEKAMFAALVEQEDPDLLDWFMEVSEPPRPEMKTLIQKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT210107 NZ_CP104403:32036-32452 [Enterobacter hormaechei subsp. steigerwaltii]
ATGATCGTCGCTGATGCAATGAAAGCTACGCACGCCCTTGTTGCGGCCGTTCCTTTACTGGGTGAACAGCCGAGCGAGAA
AGATTATAAGGATGCGCTTGAGCTGGTTGAGTATCTCCTTATGAACGAGCCCAATAGCCCCTTGCTGGATATTGTGTGCG
CCAGAATTAGCCGTTACGAAGCTAATCGGCCAGAGATAGTCGCATTACGCAAGGAGATGGAGTCCGTTCCCGTCGGAATT
GCAGTTTTAAGAACCTTGATGGATCAATACAATCTGACGATATCGGATTTTAAGGATGAAATTGGTAGTAAATCGATGGT
TTCACGGGTTCTGAATGGTCAGAGACAGCTTACCCTGAACCATATTAAAAAGCTGGCGGCCAGATTTGGGGTATCACCTG
CGTTATTTATTGAGTGA

Structures

Antitoxin

• AlphaFold DB: N9CU98