Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Doc(toxin)
Location 686154..686716 Replicon chromosome
Accession NZ_CP079792
Organism Acinetobacter johnsonii strain AJ_082

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag EGT72_RS03295 Protein ID WP_125280299.1
Coordinates 686324..686716 (+) Length 131 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag EGT72_RS03290 Protein ID WP_125280298.1
Coordinates 686154..686324 (+) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EGT72_RS03280 (EGT72_003280) 682489..683211 - 723 WP_125280296.1 folate-binding Fe/S cluster repair protein -
EGT72_RS03285 (EGT72_003285) 683473..686079 + 2607 WP_125280297.1 Fe/S-dependent 2-methylisocitrate dehydratase AcnD -
EGT72_RS03290 (EGT72_003290) 686154..686324 + 171 WP_125280298.1 acetyltransferase Antitoxin
EGT72_RS03295 (EGT72_003295) 686324..686716 + 393 WP_125280299.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
EGT72_RS18555 686713..686835 + 123 WP_267461041.1 hypothetical protein -
EGT72_RS03300 (EGT72_003300) 686906..688666 + 1761 WP_125280300.1 AAA family ATPase -
EGT72_RS03305 (EGT72_003305) 688946..689089 + 144 WP_004695201.1 zinc ribbon-containing protein -
EGT72_RS03310 (EGT72_003310) 689208..689783 + 576 WP_125280301.1 DUF4126 domain-containing protein -
EGT72_RS03315 (EGT72_003315) 690016..690222 + 207 WP_005400272.1 hypothetical protein -
EGT72_RS03320 (EGT72_003320) 690304..690657 - 354 WP_125280302.1 hypothetical protein -
EGT72_RS03325 (EGT72_003325) 690873..691574 + 702 WP_171428507.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(37-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14069.88 Da        Isoelectric Point: 4.0582

>T210106 WP_125280299.1 NZ_CP079792:686324-686716 [Acinetobacter johnsonii]
MNIICFPFERVIEINAFILATEKGMKGASDVGKLQGALARVDNAIVYEGLDDVFEIAAKYASSIANAHALSDANKRTGLA
VALEYLSLNDYELLQDNELLADAVRDLVIGEVTENDFADILYAHYVANGG

Download         Length: 393 bp

>T210106 NZ_CP104402:c75710-75186 [Enterobacter hormaechei subsp. steigerwaltii]
GTGGCCAACCTGACCATTGAGATGTTTTCAGAAGAGGCTGTATATGATTTCTCATGCTTCGACTGCGGAGAAACGTCTCT
CAATGATTTTCTTAACAATCGCCTCGCCCAGCAACACAGCGGGCGTATATTACGCGGATATCTGCTTCTGACGAGAGATC
CGATACCGAAAGTGATGGGGTTTTACACGTTGTCCGGGAGCTGCTTTGCAAGAAACACGCTTCCTTCCAACACTCAACAG
CGTAAAGTCCCCTATTCCGACGCCCCAAGCGTTACGCTCGGTCGTCTGGCAATAGACAAAAGTATCCAGCGACAAGGGTA
TGGGGAAACGCTGGTGGCACATGCGATGAAAGTGGTATACCGGGCTTCCCTGGCCGTTGGGATCTACGCTTTGTTTGTTG
ACGCCAAAAATGAGAATGCGATGCGGTTTTATAAGCAGTTAGGCTTTACCCCTCTTACGGGTGATAACGCCAATTCGCTG
TTCTATCCCACAAAAGGCATTGAGAAGTTGTTTGGTGGAAAATAA

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6316.39 Da        Isoelectric Point: 10.9041

>AT210106 WP_125280298.1 NZ_CP079792:686154-686324 [Acinetobacter johnsonii]
MNKKVEKYGVAAVERPKIQATKQLDLSGDTGRQIVKSETKLALRTHSKTFKRLADM

Download         Length: 171 bp

>AT210106 NZ_CP104402:c75983-75714 [Enterobacter hormaechei subsp. steigerwaltii]
ATGTCAGCACTGAAAAAACAGCGCATCGATCTCAGATTAACCGACGACGACAAGAGCATGATCGAAGAAGCTGCGGCAAT
GACCAACCAGACAATTACTCAGTTTATGGTTGCCAGTGCCTCTGAACGTGCTGCGGAAGTGATAGAGCAACATCGTCGCC
TGATTCTTAGCGAAGAGTCATGGAATATAGTGATGGATGCCATCAGTAACCCGCCTGCACCGAATGATAGGCTGAAACGA
GCTGCCGAGCGTCTACAAAGCATGGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References