Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | phd-doc/Doc(toxin) |
Location | 686154..686716 | Replicon | chromosome |
Accession | NZ_CP079792 | ||
Organism | Acinetobacter johnsonii strain AJ_082 |
Toxin (Protein)
Gene name | doc | Uniprot ID | - |
Locus tag | EGT72_RS03295 | Protein ID | WP_125280299.1 |
Coordinates | 686324..686716 (+) | Length | 131 a.a. |
Antitoxin (Protein)
Gene name | phd | Uniprot ID | - |
Locus tag | EGT72_RS03290 | Protein ID | WP_125280298.1 |
Coordinates | 686154..686324 (+) | Length | 57 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
EGT72_RS03280 (EGT72_003280) | 682489..683211 | - | 723 | WP_125280296.1 | folate-binding Fe/S cluster repair protein | - |
EGT72_RS03285 (EGT72_003285) | 683473..686079 | + | 2607 | WP_125280297.1 | Fe/S-dependent 2-methylisocitrate dehydratase AcnD | - |
EGT72_RS03290 (EGT72_003290) | 686154..686324 | + | 171 | WP_125280298.1 | acetyltransferase | Antitoxin |
EGT72_RS03295 (EGT72_003295) | 686324..686716 | + | 393 | WP_125280299.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin |
EGT72_RS18555 | 686713..686835 | + | 123 | WP_267461041.1 | hypothetical protein | - |
EGT72_RS03300 (EGT72_003300) | 686906..688666 | + | 1761 | WP_125280300.1 | AAA family ATPase | - |
EGT72_RS03305 (EGT72_003305) | 688946..689089 | + | 144 | WP_004695201.1 | zinc ribbon-containing protein | - |
EGT72_RS03310 (EGT72_003310) | 689208..689783 | + | 576 | WP_125280301.1 | DUF4126 domain-containing protein | - |
EGT72_RS03315 (EGT72_003315) | 690016..690222 | + | 207 | WP_005400272.1 | hypothetical protein | - |
EGT72_RS03320 (EGT72_003320) | 690304..690657 | - | 354 | WP_125280302.1 | hypothetical protein | - |
EGT72_RS03325 (EGT72_003325) | 690873..691574 | + | 702 | WP_171428507.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 131 a.a. Molecular weight: 14069.88 Da Isoelectric Point: 4.0582
>T210106 WP_125280299.1 NZ_CP079792:686324-686716 [Acinetobacter johnsonii]
MNIICFPFERVIEINAFILATEKGMKGASDVGKLQGALARVDNAIVYEGLDDVFEIAAKYASSIANAHALSDANKRTGLA
VALEYLSLNDYELLQDNELLADAVRDLVIGEVTENDFADILYAHYVANGG
MNIICFPFERVIEINAFILATEKGMKGASDVGKLQGALARVDNAIVYEGLDDVFEIAAKYASSIANAHALSDANKRTGLA
VALEYLSLNDYELLQDNELLADAVRDLVIGEVTENDFADILYAHYVANGG
Download Length: 393 bp
>T210106 NZ_CP104402:c75710-75186 [Enterobacter hormaechei subsp. steigerwaltii]
GTGGCCAACCTGACCATTGAGATGTTTTCAGAAGAGGCTGTATATGATTTCTCATGCTTCGACTGCGGAGAAACGTCTCT
CAATGATTTTCTTAACAATCGCCTCGCCCAGCAACACAGCGGGCGTATATTACGCGGATATCTGCTTCTGACGAGAGATC
CGATACCGAAAGTGATGGGGTTTTACACGTTGTCCGGGAGCTGCTTTGCAAGAAACACGCTTCCTTCCAACACTCAACAG
CGTAAAGTCCCCTATTCCGACGCCCCAAGCGTTACGCTCGGTCGTCTGGCAATAGACAAAAGTATCCAGCGACAAGGGTA
TGGGGAAACGCTGGTGGCACATGCGATGAAAGTGGTATACCGGGCTTCCCTGGCCGTTGGGATCTACGCTTTGTTTGTTG
ACGCCAAAAATGAGAATGCGATGCGGTTTTATAAGCAGTTAGGCTTTACCCCTCTTACGGGTGATAACGCCAATTCGCTG
TTCTATCCCACAAAAGGCATTGAGAAGTTGTTTGGTGGAAAATAA
GTGGCCAACCTGACCATTGAGATGTTTTCAGAAGAGGCTGTATATGATTTCTCATGCTTCGACTGCGGAGAAACGTCTCT
CAATGATTTTCTTAACAATCGCCTCGCCCAGCAACACAGCGGGCGTATATTACGCGGATATCTGCTTCTGACGAGAGATC
CGATACCGAAAGTGATGGGGTTTTACACGTTGTCCGGGAGCTGCTTTGCAAGAAACACGCTTCCTTCCAACACTCAACAG
CGTAAAGTCCCCTATTCCGACGCCCCAAGCGTTACGCTCGGTCGTCTGGCAATAGACAAAAGTATCCAGCGACAAGGGTA
TGGGGAAACGCTGGTGGCACATGCGATGAAAGTGGTATACCGGGCTTCCCTGGCCGTTGGGATCTACGCTTTGTTTGTTG
ACGCCAAAAATGAGAATGCGATGCGGTTTTATAAGCAGTTAGGCTTTACCCCTCTTACGGGTGATAACGCCAATTCGCTG
TTCTATCCCACAAAAGGCATTGAGAAGTTGTTTGGTGGAAAATAA
Antitoxin
Download Length: 57 a.a. Molecular weight: 6316.39 Da Isoelectric Point: 10.9041
>AT210106 WP_125280298.1 NZ_CP079792:686154-686324 [Acinetobacter johnsonii]
MNKKVEKYGVAAVERPKIQATKQLDLSGDTGRQIVKSETKLALRTHSKTFKRLADM
MNKKVEKYGVAAVERPKIQATKQLDLSGDTGRQIVKSETKLALRTHSKTFKRLADM
Download Length: 171 bp
>AT210106 NZ_CP104402:c75983-75714 [Enterobacter hormaechei subsp. steigerwaltii]
ATGTCAGCACTGAAAAAACAGCGCATCGATCTCAGATTAACCGACGACGACAAGAGCATGATCGAAGAAGCTGCGGCAAT
GACCAACCAGACAATTACTCAGTTTATGGTTGCCAGTGCCTCTGAACGTGCTGCGGAAGTGATAGAGCAACATCGTCGCC
TGATTCTTAGCGAAGAGTCATGGAATATAGTGATGGATGCCATCAGTAACCCGCCTGCACCGAATGATAGGCTGAAACGA
GCTGCCGAGCGTCTACAAAGCATGGAGTAA
ATGTCAGCACTGAAAAAACAGCGCATCGATCTCAGATTAACCGACGACGACAAGAGCATGATCGAAGAAGCTGCGGCAAT
GACCAACCAGACAATTACTCAGTTTATGGTTGCCAGTGCCTCTGAACGTGCTGCGGAAGTGATAGAGCAACATCGTCGCC
TGATTCTTAGCGAAGAGTCATGGAATATAGTGATGGATGCCATCAGTAACCCGCCTGCACCGAATGATAGGCTGAAACGA
GCTGCCGAGCGTCTACAAAGCATGGAGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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