Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-RelB |
| Location | 1154490..1155016 | Replicon | chromosome |
| Accession | NZ_CP079772 | ||
| Organism | Escherichia coli strain GS04 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | S1EXL1 |
| Locus tag | KYX57_RS05755 | Protein ID | WP_000323025.1 |
| Coordinates | 1154729..1155016 (+) | Length | 96 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | S1F6D3 |
| Locus tag | KYX57_RS05750 | Protein ID | WP_000534858.1 |
| Coordinates | 1154490..1154729 (+) | Length | 80 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KYX57_RS05720 (1149827) | 1149827..1150316 | + | 490 | Protein_1120 | class I SAM-dependent methyltransferase | - |
| KYX57_RS05725 (1150794) | 1150794..1151079 | + | 286 | Protein_1121 | hypothetical protein | - |
| KYX57_RS05730 (1151869) | 1151869..1152918 | + | 1050 | Protein_1122 | ISNCY family transposase | - |
| KYX57_RS05735 (1153039) | 1153039..1153188 | + | 150 | WP_011443592.1 | protein YdfW | - |
| KYX57_RS05740 (1153625) | 1153625..1153957 | - | 333 | WP_001317460.1 | FlxA-like family protein | - |
| KYX57_RS05745 (1154160) | 1154160..1154465 | - | 306 | WP_001326990.1 | protein YdfV | - |
| KYX57_RS05750 (1154490) | 1154490..1154729 | + | 240 | WP_000534858.1 | type II toxin-antitoxin system antitoxin RelB | Antitoxin |
| KYX57_RS05755 (1154729) | 1154729..1155016 | + | 288 | WP_000323025.1 | type II toxin-antitoxin system mRNA interferase RelE | Toxin |
| KYX57_RS05760 (1155088) | 1155088..1155243 | + | 156 | WP_000813254.1 | type I toxin-antitoxin system toxin HokD | - |
| KYX57_RS05765 (1155460) | 1155460..1155711 | + | 252 | WP_000980994.1 | protein Rem | - |
| KYX57_RS05770 (1155778) | 1155778..1156056 | + | 279 | WP_012304870.1 | hypothetical protein | - |
| KYX57_RS05775 (1156058) | 1156058..1157107 | + | 1050 | WP_259482664.1 | DUF968 domain-containing protein | - |
| KYX57_RS05780 (1157121) | 1157121..1157873 | + | 753 | WP_001047135.1 | antitermination protein | - |
| KYX57_RS05785 (1158151) | 1158151..1158240 | - | 90 | WP_120795389.1 | hypothetical protein | - |
| KYX57_RS05790 (1158295) | 1158295..1158507 | - | 213 | WP_000087756.1 | cold shock-like protein CspF | - |
| KYX57_RS05795 (1158808) | 1158808..1159023 | + | 216 | WP_000066484.1 | cold shock-like protein CspB | - |
| KYX57_RS05800 (1159387) | 1159387..1159557 | - | 171 | WP_001405948.1 | putative zinc-binding protein YnfU | - |
| KYX57_RS05805 (1159777) | 1159777..1159992 | + | 216 | WP_000839590.1 | phage lysis protein EssD | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1136190..1193857 | 57667 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 96 a.a. Molecular weight: 11225.22 Da Isoelectric Point: 10.1967
>T210024 WP_000323025.1 NZ_CP079772:1154729-1155016 [Escherichia coli]
MAYFLDFDERALKEWRKLGSTVREQLKKKLVEVLESPRIEANKLRGMPDCYKIKLRSSGYRLVYQVIDEKVVVFVISVGK
RERSEVYSEAVKRIL
MAYFLDFDERALKEWRKLGSTVREQLKKKLVEVLESPRIEANKLRGMPDCYKIKLRSSGYRLVYQVIDEKVVVFVISVGK
RERSEVYSEAVKRIL
Download Length: 288 bp
>T210024 NZ_CP104367:c91142-90837 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATGCAGTTTAAGGTTTACACCTGTAAAAGGGAGAGTCGCTACCGGCTGTTTGTGGACGTGCAGAGCGACATCATTGACAC
CCCCGGACGGCGGATGGCTGTCCCGCTGGTCAGCGCCCGTCTGCTGTCGGAAAAGGTTCCCCGCGATCTTTACCCGGTGA
TGCATATCGGGGATGAGCCTTACCGCCTGCTGACCACGGATATGACCAGTGTGCCGGCCACCGTCATCGGGGAAGAGGTG
GCCGATCTCAGCCTCCGGGAGAACGATATCAAAAACGCCATTAACCTGATGTTCCGGGGGATCTGA
ATGCAGTTTAAGGTTTACACCTGTAAAAGGGAGAGTCGCTACCGGCTGTTTGTGGACGTGCAGAGCGACATCATTGACAC
CCCCGGACGGCGGATGGCTGTCCCGCTGGTCAGCGCCCGTCTGCTGTCGGAAAAGGTTCCCCGCGATCTTTACCCGGTGA
TGCATATCGGGGATGAGCCTTACCGCCTGCTGACCACGGATATGACCAGTGTGCCGGCCACCGTCATCGGGGAAGAGGTG
GCCGATCTCAGCCTCCGGGAGAACGATATCAAAAACGCCATTAACCTGATGTTCCGGGGGATCTGA
Antitoxin
Download Length: 80 a.a. Molecular weight: 9071.48 Da Isoelectric Point: 4.5230
>AT210024 WP_000534858.1 NZ_CP079772:1154490-1154729 [Escherichia coli]
MGSINLRIDDELKARSYAALEKMGVTPSEALRLMLEYIADNERLPFKQTLLSDEDAELVEIVKERLRNPKPVRVTLDEL
MGSINLRIDDELKARSYAALEKMGVTPSEALRLMLEYIADNERLPFKQTLLSDEDAELVEIVKERLRNPKPVRVTLDEL
Download Length: 240 bp
>AT210024 NZ_CP104367:c91362-91144 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATGAAGCAGCGAATTACAGTGACAGTGGACAGCGACAGCTATCAGCTGCTCAAGGCATACGACGTGAATATCTCCGGTCT
GGTCAGTACGACCATGCAGAACGAAGCCCGCCGTCTGCGAGCCGAACGCTGGCAGGAAGAAAATCGGGAAGGTATGGCTG
AGGTGGCCAGCTTTATAGAGGCTAACGGATCGTTTGCTGACGACAACAGGAACTGGTGA
ATGAAGCAGCGAATTACAGTGACAGTGGACAGCGACAGCTATCAGCTGCTCAAGGCATACGACGTGAATATCTCCGGTCT
GGTCAGTACGACCATGCAGAACGAAGCCCGCCGTCTGCGAGCCGAACGCTGGCAGGAAGAAAATCGGGAAGGTATGGCTG
AGGTGGCCAGCTTTATAGAGGCTAACGGATCGTTTGCTGACGACAACAGGAACTGGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|