Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1636606..1636751 Replicon chromosome
Accession NZ_CP079762
Organism Klebsiella pneumoniae strain JP20

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1636613..1636715 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1636606..1636751 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KYE76_RS07965 1632360..1632599 + 240 WP_002911393.1 YebV family protein -
KYE76_RS07970 1632697..1632888 + 192 WP_002911395.1 YebW family protein -
KYE76_RS07975 1632885..1633529 - 645 WP_116440814.1 protein-serine/threonine phosphatase -
KYE76_RS07980 1633686..1634642 + 957 WP_162866168.1 VirK/YbjX family protein -
KYE76_RS07985 1634652..1635857 - 1206 Protein_1588 IS4-like element ISVsa5 family transposase -
KYE76_RS07990 1636094..1636237 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 1636606..1636751 + 146 - - Antitoxin
- 1636613..1636715 - 103 - - Toxin
KYE76_RS07995 1636874..1637212 - 339 WP_002911404.1 YebY family protein -
KYE76_RS08000 1637229..1638098 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
KYE76_RS08005 1638102..1638476 - 375 WP_004151448.1 CopC domain-containing protein YobA -
KYE76_RS08010 1638589..1638819 + 231 WP_002911406.1 DNA polymerase III subunit theta -
KYE76_RS08015 1638898..1639557 + 660 WP_020324964.1 exodeoxyribonuclease X -
KYE76_RS08020 1639561..1641621 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T209946 NZ_CP079762:c1636715-1636613 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT209946 NZ_CP079762:1636606-1636751 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References