Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 3683450..3684276 Replicon chromosome
Accession NC_005125
Organism Gloeobacter violaceus PCC 7421

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag GLL_RS17925 Protein ID WP_193345473.1
Coordinates 3683755..3684276 (+) Length 174 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag GLL_RS17920 Protein ID WP_011143463.1
Coordinates 3683450..3683737 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GLL_RS17900 3678972..3680492 - 1521 WP_011143459.1 SagB/ThcOx family dehydrogenase -
GLL_RS17905 3680528..3681112 - 585 WP_164929301.1 M23 family metallopeptidase -
GLL_RS17910 3681230..3682171 + 942 WP_011143461.1 ABC transporter ATP-binding protein -
GLL_RS17915 3682168..3683379 + 1212 WP_011143462.1 ABC transporter permease -
GLL_RS17920 3683450..3683737 + 288 WP_011143463.1 DUF1778 domain-containing protein Antitoxin
GLL_RS17925 3683755..3684276 + 522 WP_193345473.1 GNAT family N-acetyltransferase Toxin
GLL_RS17930 3684594..3684779 - 186 WP_011143465.1 CPXCG motif-containing cysteine-rich protein -
GLL_RS17935 3684799..3685719 - 921 WP_011143466.1 class I SAM-dependent methyltransferase -
GLL_RS17940 3685878..3686483 + 606 WP_011143467.1 class I SAM-dependent methyltransferase -
GLL_RS17945 3686490..3687812 - 1323 WP_011143468.1 LCP family protein -
GLL_RS17950 3687900..3688841 + 942 WP_011143469.1 NDP-sugar synthase -
GLL_RS17955 3688814..3689107 - 294 WP_164929302.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(46-145)

Antitoxin

Vibrio phage ICP1, Orf50

(1-95)


Sequences

Toxin        


Download         Length: 174 a.a.        Molecular weight: 18895.20 Da        Isoelectric Point: 9.8841

>T20986 WP_193345473.1 NC_005125:3683755-3684276 [Gloeobacter violaceus PCC 7421]
VESVKPSAPELLAAHHELVGFCCKELALNEWLVKRARQNQNTGASRTFVVCIGVRVVAYYCLAMGSVSSHIAPGKVRRNM
PDPIPVAVIGRLAVDKSYEGQGYGKGLVKDAVQRVIQMSQVIGVRAILVHAVSVQAKSFYLNRGFLESPVEAMTLMLPMQ
DALRIYAVAFRPS

Download         Length: 522 bp

>T20986 NC_005125:3683755-3684276 [Gloeobacter violaceus PCC 7421]
GTGGAATCCGTTAAGCCCAGTGCACCGGAATTATTGGCGGCGCATCACGAACTTGTCGGGTTCTGCTGCAAGGAATTGGC
ATTGAACGAATGGCTCGTAAAGCGTGCAAGGCAGAATCAAAACACGGGCGCTTCGCGCACTTTTGTCGTCTGCATTGGAG
TTCGGGTTGTGGCTTATTACTGCCTGGCTATGGGCTCGGTCAGTTCGCACATCGCTCCGGGCAAAGTCCGTCGTAATATG
CCGGATCCGATTCCCGTAGCAGTGATTGGTCGGCTTGCAGTGGACAAGAGCTATGAAGGGCAAGGGTACGGCAAGGGGTT
GGTGAAAGACGCGGTGCAGCGGGTGATTCAGATGAGCCAGGTAATTGGGGTACGGGCGATCCTGGTGCATGCCGTCTCTG
TCCAGGCCAAATCGTTTTACCTCAACCGTGGTTTCTTGGAGTCGCCCGTAGAAGCGATGACCTTGATGTTGCCGATGCAG
GACGCGCTGCGAATCTACGCTGTTGCCTTCCGGCCATCCTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10475.89 Da        Isoelectric Point: 4.5112

>AT20986 WP_011143463.1 NC_005125:3683450-3683737 [Gloeobacter violaceus PCC 7421]
MAASDGNLRGKDVVINLRAEQGQRELIDRAAKVLGKNRSDFMIESALRAAETVLLDRVFFDLDEASYARFVEALESPPAV
NARLLATLTAEAPWE

Download         Length: 288 bp

>AT20986 NC_005125:3683450-3683737 [Gloeobacter violaceus PCC 7421]
ATGGCGGCTTCAGACGGAAACCTTCGAGGGAAAGACGTGGTGATCAACTTGCGGGCCGAGCAGGGCCAGCGCGAGCTGAT
CGACCGGGCAGCGAAGGTGCTCGGTAAAAACCGCTCCGATTTTATGATCGAGAGCGCCTTGCGCGCTGCCGAAACGGTTT
TGCTCGATCGGGTGTTTTTTGATCTGGACGAAGCCTCTTACGCACGGTTCGTGGAGGCATTGGAGAGTCCCCCGGCTGTG
AATGCACGTTTGCTCGCCACCCTCACTGCTGAAGCTCCCTGGGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References