Detailed information of TA system TA020984

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 2885604..2886445
• Replicon: chromosome
• Accession: NC_005125
• Organism: Gloeobacter violaceus PCC 7421

Toxin (Protein)

• Gene name: -
• Uniprot ID: Q7NH12
• Locus tag: GLL_RS14035
• Protein ID: WP_011142719.1
• Coordinates: 2885888..2886445 (+)
• Length: 186 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: GLL_RS14030
• Protein ID: WP_197530007.1
• Coordinates: 2885604..2885891 (+)
• Length: 96 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GLL_RS14015	2881367..2882500	-	1134	WP_011142715.1	hypothetical protein	-
GLL_RS14020	2882628..2883089	+	462	WP_011142716.1	hypothetical protein	-
GLL_RS14025	2883159..2885453	+	2295	WP_011142717.1	tetratricopeptide repeat protein	-
GLL_RS14030	2885604..2885891	+	288	WP_197530007.1	MbcA/ParS/Xre antitoxin family protein	Antitoxin
GLL_RS14035	2885888..2886445	+	558	WP_011142719.1	RES domain-containing protein	Toxin
GLL_RS14040	2886523..2886873	-	351	WP_164929087.1	hypothetical protein	-
GLL_RS14045	2886870..2887166	-	297	WP_011142720.1	hypothetical protein	-
GLL_RS14050	2887319..2889136	+	1818	WP_011142721.1	DUF885 domain-containing protein	-
GLL_RS14055	2889178..2889894	+	717	WP_011142722.1	hypothetical protein	-
GLL_RS14060	2889898..2890353	+	456	WP_011142723.1	putative molybdenum carrier protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (23-178)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (42-92)

Sequences

Toxin

Protein

• Length: 186 a.a.
• Molecular weight: 20444.45 Da
• Isoelectric Point: 6.3248

>T20984 WP_011142719.1 NC_005125:2885888-2886445 [Gloeobacter violaceus PCC 7421]
MNFGAEAGAALPLRACLLYEKRCWRILAPRWAYQPLSGEGAARNGGRWNPKGVPALYLSESIDTAFAEYQQTLYVRPGTF
CAYRLLVAGVVDLCDPTVLVELGVNEETLPCAWREIALIRKDTPPTWTLASKLFAAGASGVRVPSAQFNGGINIVLWRWN
DAPERQVEVLDPIGDLPKDQRSWSP

Nucleotide

• Length: 558 bp

>T20984 NC_005125:2885888-2886445 [Gloeobacter violaceus PCC 7421]
TTGAACTTCGGTGCCGAAGCCGGAGCGGCCCTTCCCCTGCGCGCCTGCTTGTTGTACGAGAAAAGGTGCTGGCGCATCCT
TGCCCCGAGATGGGCGTATCAACCACTCTCGGGGGAGGGGGCGGCCCGCAATGGCGGCAGGTGGAATCCCAAAGGCGTGC
CTGCTTTGTATCTCTCCGAATCCATCGACACAGCGTTCGCGGAGTATCAGCAGACACTGTACGTGCGACCGGGCACGTTT
TGCGCCTACCGCCTTCTGGTGGCGGGCGTGGTAGATCTGTGTGATCCCACGGTGCTCGTTGAACTTGGGGTAAACGAGGA
AACTTTGCCATGCGCGTGGAGGGAAATCGCCCTTATTCGCAAGGACACTCCCCCGACCTGGACGCTCGCAAGCAAGCTGT
TTGCGGCCGGGGCCAGCGGTGTGCGGGTGCCGTCGGCCCAGTTCAATGGCGGAATCAACATCGTGCTGTGGCGATGGAAC
GATGCACCCGAAAGACAGGTGGAAGTCCTCGATCCCATTGGCGATCTGCCGAAAGATCAACGCTCGTGGAGTCCCTAA

Antitoxin

Protein

• Length: 96 a.a.
• Molecular weight: 10523.16 Da
• Isoelectric Point: 8.6422

>AT20984 WP_197530007.1 NC_005125:2885604-2885891 [Gloeobacter violaceus PCC 7421]
MKLPMTDLAKIVHLHRNTLSRRPQSPEVQSRLGRVAKIIARAAAMIGGEANRAVIWFRFEPLPGFDHKTAAQLVAEGHAD
AVETYLDMLDDGVYA

Nucleotide

• Length: 288 bp

>AT20984 NC_005125:2885604-2885891 [Gloeobacter violaceus PCC 7421]
ATGAAGCTGCCGATGACGGACCTTGCGAAAATCGTGCACTTGCACCGCAACACCCTCAGCCGTCGGCCGCAATCGCCTGA
GGTGCAGAGCAGGCTCGGGCGGGTGGCCAAGATCATCGCCCGCGCCGCCGCAATGATTGGGGGGGAGGCGAACCGGGCTG
TGATCTGGTTTCGCTTTGAGCCGCTACCGGGCTTTGACCACAAAACTGCGGCGCAACTGGTGGCTGAGGGGCACGCTGAT
GCAGTGGAGACCTACCTCGATATGCTTGACGACGGGGTATACGCTTGA

Structures

Toxin

• AlphaFold DB: Q7NH12