Detailed information of TA system TA020983

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEi(antitoxin)
• Location: 2823578..2824386
• Replicon: chromosome
• Accession: NC_005125
• Organism: Gloeobacter violaceus PCC 7421

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: Q7NH75
• Locus tag: GLL_RS22990
• Protein ID: WP_011142656.1
• Coordinates: 2824183..2824386 (+)
• Length: 68 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: Q7NH76
• Locus tag: GLL_RS13740
• Protein ID: WP_011142655.1
• Coordinates: 2823578..2824186 (+)
• Length: 203 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GLL_RS13725	2819928..2820149	+	222	WP_164929075.1	hypothetical protein	-
GLL_RS13730	2820214..2822937	+	2724	WP_011142653.1	hypothetical protein	-
GLL_RS13735	2822990..2823244	+	255	WP_011142654.1	UPF0175 family protein	-
GLL_RS13740	2823578..2824186	+	609	WP_011142655.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin
GLL_RS22990	2824183..2824386	+	204	WP_011142656.1	hypothetical protein	Toxin
GLL_RS13745	2824396..2825106	+	711	WP_197530003.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	-
GLL_RS13750	2825263..2825796	-	534	WP_164929701.1	Uma2 family endonuclease	-
GLL_RS13755	2825985..2827217	-	1233	WP_011142659.1	type II secretion system F family protein	-
GLL_RS13760	2827238..2828395	-	1158	WP_011142660.1	type IV pilus twitching motility protein PilT	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	2811092..2825106	14014

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (18-53)

Sequences

Toxin

Protein

• Length: 68 a.a.
• Molecular weight: 8011.25 Da
• Isoelectric Point: 10.5294

>T20983 WP_011142656.1 NC_005125:2824183-2824386 [Gloeobacter violaceus PCC 7421]
MKDMAASVRDRLYAEHRRRGEEFQFLVTRYALERVLYRLGRSRHVESFVLKGAMLFAIWADEPHRAT

Nucleotide

• Length: 204 bp

>T20983 NC_005125:2824183-2824386 [Gloeobacter violaceus PCC 7421]
ATGAAGGACATGGCCGCCTCCGTGCGCGACCGCCTGTACGCGGAGCACCGGCGTCGGGGAGAGGAGTTTCAGTTTCTTGT
GACGCGCTACGCCCTGGAGCGAGTGCTTTACCGGCTTGGCCGCTCCCGGCACGTCGAGAGCTTCGTCCTCAAAGGAGCGA
TGCTCTTTGCCATCTGGGCCGACGAACCGCACCGGGCCACCTAG

Antitoxin

Protein

• Length: 203 a.a.
• Molecular weight: 22959.41 Da
• Isoelectric Point: 8.1699

>AT20983 WP_011142655.1 NC_005125:2823578-2824186 [Gloeobacter violaceus PCC 7421]
MATDSVSASRECLQNRAIFRFKDLNGSGLHRSSLRRLEEAGQIEQIARGIYRNTRADITTHHSLAVASTLVHRGIVCLLS
ALRFHELTTQAPFEVWMAIDHKAYRPADLAIPLRVVWFSGEAFTSGVEEYVVEGVPVRVYCLAKTVTDCFKYRNKIGLDV
ALEALRECRREGRCSMDELWHYARICRVANVMRPYLEALAET

Nucleotide

• Length: 609 bp

>AT20983 NC_005125:2823578-2824186 [Gloeobacter violaceus PCC 7421]
ATGGCTACTGACTCTGTTTCAGCGTCCCGTGAATGCCTGCAGAACCGGGCTATTTTCAGGTTCAAGGATCTCAATGGTTC
CGGCCTCCATCGATCTAGTCTGCGGCGTCTGGAGGAAGCAGGACAGATCGAGCAGATTGCCCGCGGCATTTACAGGAACA
CCAGGGCAGACATCACCACCCACCACAGCCTGGCAGTCGCTTCTACGCTAGTTCACCGCGGGATCGTCTGCCTGCTGTCG
GCTCTGCGCTTTCACGAACTGACCACCCAGGCGCCCTTTGAAGTCTGGATGGCCATTGACCACAAAGCCTATCGTCCCGC
CGACCTGGCGATCCCTCTGCGGGTTGTTTGGTTTTCCGGCGAGGCATTCACCTCCGGTGTTGAAGAGTATGTGGTGGAAG
GAGTGCCGGTGCGGGTGTACTGTCTGGCCAAGACCGTGACCGATTGCTTCAAGTACCGCAATAAGATCGGCCTGGATGTG
GCTCTCGAAGCCCTTCGTGAATGCCGCCGTGAGGGGCGTTGCTCGATGGATGAGCTGTGGCATTACGCCCGTATCTGCCG
GGTGGCAAACGTCATGCGCCCCTACCTGGAGGCGCTGGCGGAAACATGA

Structures

Toxin

• AlphaFold DB: Q7NH75

Antitoxin

• AlphaFold DB: Q7NH76