20979

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 215766..216346 Replicon chromosome
Accession NC_005070
Organism Synechococcus sp. WH 8102

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag TX72_RS01065 Protein ID WP_049692756.1
Coordinates 215766..216128 (-) Length 121 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag TX72_RS01070 Protein ID WP_042502788.1
Coordinates 216128..216346 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
TX72_RS01050 (SYNW0211) 211865..212620 + 756 WP_011127087.1 ATP-binding cassette domain-containing protein -
TX72_RS01055 (SYNW0212) 212626..213549 + 924 WP_011127088.1 MCE family protein -
TX72_RS01060 (SYNW0213) 213608..215716 - 2109 WP_011127089.1 magnesium chelatase ATPase subunit D -
TX72_RS01065 (SYNW0214) 215766..216128 - 363 WP_049692756.1 type II toxin-antitoxin system VapC family toxin Toxin
TX72_RS01070 (SYNW0215) 216128..216346 - 219 WP_042502788.1 ribbon-helix-helix domain-containing protein Antitoxin
TX72_RS01075 (SYNW0216) 216293..216898 + 606 WP_083810649.1 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase -
TX72_RS01080 (SYNW0217) 216840..218582 - 1743 WP_148228838.1 ATP-binding cassette domain-containing protein -
TX72_RS01085 (SYNW0218) 218632..219195 + 564 WP_011127094.1 NUDIX hydrolase -
TX72_RS01090 (SYNW0219) 219192..220625 + 1434 WP_011127095.1 deoxyribodipyrimidine photo-lyase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-104)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-38)


Sequences

Toxin        


Download         Length: 121 a.a.        Molecular weight: 13491.46 Da        Isoelectric Point: 5.6542

>T20979 WP_049692756.1 NC_005070:c216128-215766 [Synechococcus sp. WH 8102]
MRLLLDTNVLIDVLKGETTARDWLEEQQQPAVSVITWIEVLVGCRTAESQTVEAWLDSFERLSLDRDVARESVQARRRHG
LKVPEAIILATARCHGLALATRNSKDFPLSLGDVLHPYSL

Download         Length: 363 bp

>T20979 NC_005070:c216128-215766 [Synechococcus sp. WH 8102]
ATGCGACTGCTCCTCGACACCAATGTGCTGATCGACGTCCTGAAAGGAGAAACCACGGCACGCGACTGGCTTGAAGAGCA
GCAGCAGCCCGCCGTCAGCGTGATCACCTGGATCGAAGTGCTGGTCGGCTGCCGCACCGCGGAAAGCCAGACCGTGGAAG
CCTGGCTGGATTCCTTCGAGCGGCTTTCACTGGACCGCGACGTCGCGCGGGAATCTGTGCAGGCCCGCCGGCGGCATGGT
CTCAAAGTGCCTGAAGCGATCATCCTGGCCACGGCCCGTTGCCATGGCCTGGCCCTGGCCACGCGCAACAGCAAGGACTT
CCCCCTCAGCCTGGGCGACGTGCTGCACCCCTACTCACTCTGA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8498.57 Da        Isoelectric Point: 6.8701

>AT20979 WP_042502788.1 NC_005070:c216346-216128 [Synechococcus sp. WH 8102]
MRTIIDLPEDERAVLDAHCRQRGLSRAAAIREALHLWLQHQHPRSADVFGLWRDRNADALTLESELRQEWTR

Download         Length: 219 bp

>AT20979 NC_005070:c216346-216128 [Synechococcus sp. WH 8102]
ATGCGCACGATCATCGACCTCCCTGAGGACGAACGCGCTGTGCTCGATGCCCATTGTCGTCAGCGGGGCCTCTCCCGTGC
CGCAGCGATCCGCGAAGCGCTGCACCTCTGGCTGCAACACCAGCACCCCCGATCCGCAGACGTGTTCGGCCTCTGGCGCG
ACCGCAACGCTGATGCCCTGACGCTCGAATCCGAGCTGCGGCAGGAATGGACGCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References