209782

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ygfYX/Cpta(toxin)
Location 3747677..3748346 Replicon chromosome
Accession NZ_CP079718
Organism Shewanella xiamenensis strain HD6416

Toxin (Protein)


Gene name ygfX Uniprot ID -
Locus tag KXJ80_RS17620 Protein ID WP_259474477.1
Coordinates 3747677..3748117 (-) Length 147 a.a.

Antitoxin (Protein)


Gene name ygfY Uniprot ID -
Locus tag KXJ80_RS17625 Protein ID WP_139122633.1
Coordinates 3748098..3748346 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KXJ80_RS17595 (KXJ80_17525) 3743091..3743564 - 474 WP_037427577.1 SoxR reducing system RseC family protein -
KXJ80_RS17600 (KXJ80_17530) 3743576..3744508 - 933 WP_037427579.1 MucB/RseB C-terminal domain-containing protein -
KXJ80_RS17605 (KXJ80_17535) 3744521..3745132 - 612 WP_218738167.1 RseA family anti-sigma factor -
KXJ80_RS17610 (KXJ80_17540) 3745174..3745752 - 579 WP_037415584.1 RNA polymerase sigma factor RpoE -
KXJ80_RS17615 (KXJ80_17545) 3745942..3747555 + 1614 WP_037415581.1 L-aspartate oxidase -
KXJ80_RS17620 3747677..3748117 - 441 WP_259474477.1 hypothetical protein Toxin
KXJ80_RS17625 (KXJ80_17550) 3748098..3748346 - 249 WP_139122633.1 succinate dehydrogenase assembly factor 2 Antitoxin
KXJ80_RS17630 (KXJ80_17555) 3748431..3749339 - 909 WP_069455412.1 transcriptional activator NhaR -
KXJ80_RS17635 (KXJ80_17560) 3749434..3749820 - 387 WP_037415577.1 hypothetical protein -
KXJ80_RS17640 (KXJ80_17565) 3749823..3750992 - 1170 WP_037415576.1 Na+/H+ antiporter NhaA -
KXJ80_RS17645 (KXJ80_17570) 3751110..3751904 - 795 WP_218738166.1 thymidylate synthase -
KXJ80_RS17650 (KXJ80_17575) 3751904..3752710 - 807 WP_037415571.1 prolipoprotein diacylglyceryl transferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(5-134)

Antitoxin

Flavinator of succinate dehydrogenase

(7-77)


Sequences

Toxin        


Download         Length: 147 a.a.        Molecular weight: 16887.75 Da        Isoelectric Point: 7.9950

>T209782 WP_259474477.1 NZ_CP079718:c3748117-3747677 [Shewanella xiamenensis]
VAELRHSFSVKASFDQRLSLVVFVCVCSTSLLLWPETDTAVLHGLRAIFAVLILGFLCSQLWQLRKWHCRFELNGQGEGW
LSTGEAFHVLQRTWVTPFICLVYYQSANKLHLLPLWADMFNDTDYRHLCRLLLKVKTQAVSQHEPI

Download         Length: 441 bp

>T209782 NZ_CP104309:1035936-1036271 [Escherichia coli O157:H7]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCCGG
ACATCGTCCGGCTGTTGTCCTGAGTCCGTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACGGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9627.21 Da        Isoelectric Point: 4.3440

>AT209782 WP_139122633.1 NZ_CP079718:c3748346-3748098 [Shewanella xiamenensis]
MELMNIARVRWACRRGMLELDVLFQPFVENVYQDLSDEDKALFIRLLECEDPELFAWFMGHEVCPDPELARMVVQVRGRA
AP

Download         Length: 249 bp

>AT209782 NZ_CP104309:1035688-1035936 [Escherichia coli O157:H7]
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References