Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | ParE-CopA/ParE-RHH |
| Location | 2414680..2415245 | Replicon | chromosome |
| Accession | NZ_CP079718 | ||
| Organism | Shewanella xiamenensis strain HD6416 | ||
Toxin (Protein)
| Gene name | parE | Uniprot ID | Q8EGZ3 |
| Locus tag | KXJ80_RS11925 | Protein ID | WP_011071641.1 |
| Coordinates | 2414680..2414973 (-) | Length | 98 a.a. |
Antitoxin (Protein)
| Gene name | copA | Uniprot ID | A0A448EM94 |
| Locus tag | KXJ80_RS11930 | Protein ID | WP_011716807.1 |
| Coordinates | 2414961..2415245 (-) | Length | 95 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KXJ80_RS11900 | 2410735..2411151 | + | 417 | WP_259474800.1 | hypothetical protein | - |
| KXJ80_RS11905 | 2411162..2411845 | + | 684 | WP_259474801.1 | hypothetical protein | - |
| KXJ80_RS11910 (KXJ80_11855) | 2411942..2412154 | + | 213 | WP_259474802.1 | AlpA family phage regulatory protein | - |
| KXJ80_RS11915 (KXJ80_11860) | 2412292..2413254 | + | 963 | WP_259474803.1 | YfjI family protein | - |
| KXJ80_RS11920 (KXJ80_11865) | 2413856..2414533 | + | 678 | WP_259474804.1 | inovirus Gp2 family protein | - |
| KXJ80_RS11925 (KXJ80_11870) | 2414680..2414973 | - | 294 | WP_011071641.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| KXJ80_RS11930 (KXJ80_11875) | 2414961..2415245 | - | 285 | WP_011716807.1 | CopG family ribbon-helix-helix protein | Antitoxin |
| KXJ80_RS11935 (KXJ80_11880) | 2415534..2416256 | - | 723 | WP_259474805.1 | lecithin retinol acyltransferase family protein | - |
| KXJ80_RS11940 (KXJ80_11885) | 2416345..2416911 | - | 567 | WP_218738601.1 | site-specific integrase | - |
| KXJ80_RS11945 (KXJ80_11890) | 2417020..2417427 | - | 408 | WP_218738600.1 | DUF2787 domain-containing protein | - |
| KXJ80_RS11950 (KXJ80_11895) | 2417617..2418030 | - | 414 | WP_218738599.1 | DUF2787 domain-containing protein | - |
| KXJ80_RS11955 (KXJ80_11900) | 2418239..2418613 | - | 375 | WP_218738598.1 | type IV toxin-antitoxin system YeeU family antitoxin | - |
| KXJ80_RS11960 (KXJ80_11905) | 2418756..2419118 | - | 363 | WP_076500087.1 | hypothetical protein | - |
| KXJ80_RS11965 (KXJ80_11910) | 2419159..2419665 | - | 507 | WP_256931108.1 | DNA repair protein RadC | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integrative and Conjugative Element | - | - | 2402670..2416911 | 14241 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 98 a.a. Molecular weight: 11125.65 Da Isoelectric Point: 5.8404
>T209781 WP_011071641.1 NZ_CP079718:c2414973-2414680 [Shewanella xiamenensis]
MPQIVFTATALRDLERLREFLRSKNPPAAQRAASAIINTIRKLESYPDIGRPIDDNDFSFRELLIDFGDTGYLAMYQYDG
GERLTVLCIRHQKEAGY
MPQIVFTATALRDLERLREFLRSKNPPAAQRAASAIINTIRKLESYPDIGRPIDDNDFSFRELLIDFGDTGYLAMYQYDG
GERLTVLCIRHQKEAGY
Download Length: 294 bp
>T209781 NZ_CP104309:890454-890861 [Escherichia coli O157:H7]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCGCTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCGCCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATAGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCGCTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCGCCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATAGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA
Antitoxin
Download Length: 95 a.a. Molecular weight: 10955.25 Da Isoelectric Point: 5.9920
>AT209781 WP_011716807.1 NZ_CP079718:c2415245-2414961 [Shewanella xiamenensis]
MSTIKPVSVKLDADIKARVEHLAETRKRSSHWMMREAIREYVEREEKREALQQEALRAWEEHQTSGLHVTGDEVVSWLES
WGSENEQAAPTCHK
MSTIKPVSVKLDADIKARVEHLAETRKRSSHWMMREAIREYVEREEKREALQQEALRAWEEHQTSGLHVTGDEVVSWLES
WGSENEQAAPTCHK
Download Length: 285 bp
>AT209781 NZ_CP104309:890207-890473 [Escherichia coli O157:H7]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTATGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCCGATC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTATGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCCGATC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|