Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2048469..2048614 Replicon chromosome
Accession NZ_CP079692
Organism Klebsiella pneumoniae subsp. pneumoniae strain WRC31_S468MPCH

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2048505..2048607 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2048469..2048614 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KW564_RS10030 2043599..2045659 + 2061 WP_004151449.1 oligopeptidase B -
KW564_RS10035 2045663..2046322 - 660 WP_002911407.1 exodeoxyribonuclease X -
KW564_RS10040 2046401..2046631 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KW564_RS10045 2046744..2047118 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KW564_RS10050 2047122..2047991 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
KW564_RS10055 2048008..2048346 + 339 WP_002911404.1 YebY family protein -
- 2048469..2048614 - 146 - - Antitoxin
- 2048505..2048607 + 103 - - Toxin
KW564_RS10060 2048983..2049126 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KW564_RS10065 2049231..2050199 - 969 WP_004151446.1 VirK/YbjX family protein -
KW564_RS10070 2050356..2051009 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
KW564_RS10075 2051006..2051197 - 192 WP_002911395.1 YebW family protein -
KW564_RS10080 2051295..2051534 - 240 WP_002911393.1 YebV family protein -
KW564_RS10085 2051650..2053083 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T209718 NZ_CP079692:2048505-2048607 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT209718 NZ_CP079692:c2048614-2048469 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References