Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2012441..2012586 Replicon chromosome
Accession NZ_CP079683
Organism Klebsiella pneumoniae subsp. pneumoniae strain WRC30_AI1547MPCH

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2012477..2012579 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2012441..2012586 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KW563_RS09785 2007571..2009631 + 2061 WP_004151449.1 oligopeptidase B -
KW563_RS09790 2009635..2010294 - 660 WP_002911407.1 exodeoxyribonuclease X -
KW563_RS09795 2010373..2010603 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KW563_RS09800 2010716..2011090 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KW563_RS09805 2011094..2011963 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
KW563_RS09810 2011980..2012318 + 339 WP_002911404.1 YebY family protein -
- 2012441..2012586 - 146 - - Antitoxin
- 2012477..2012579 + 103 - - Toxin
KW563_RS09815 2012955..2013098 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KW563_RS09820 2013203..2014171 - 969 WP_004151446.1 VirK/YbjX family protein -
KW563_RS09825 2014328..2014981 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
KW563_RS09830 2014978..2015169 - 192 WP_002911395.1 YebW family protein -
KW563_RS09835 2015267..2015506 - 240 WP_002911393.1 YebV family protein -
KW563_RS09840 2015622..2017055 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1941878..2029983 88105


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T209699 NZ_CP079683:2012477-2012579 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT209699 NZ_CP079683:c2012586-2012441 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References