Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2068068..2068213 Replicon chromosome
Accession NZ_CP079668
Organism Klebsiella pneumoniae subsp. pneumoniae strain WRC28_CMC387MPCH

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2068104..2068206 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2068068..2068213 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KW561_RS10060 2063198..2065258 + 2061 WP_004151449.1 oligopeptidase B -
KW561_RS10065 2065262..2065921 - 660 WP_043906809.1 exodeoxyribonuclease X -
KW561_RS10070 2066000..2066230 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KW561_RS10075 2066343..2066717 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KW561_RS10080 2066721..2067590 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
KW561_RS10085 2067607..2067945 + 339 WP_002911404.1 YebY family protein -
- 2068068..2068213 - 146 - - Antitoxin
- 2068104..2068206 + 103 - - Toxin
KW561_RS10090 2068582..2068725 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KW561_RS10095 2068830..2069798 - 969 WP_004151446.1 VirK/YbjX family protein -
KW561_RS10100 2069955..2070608 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
KW561_RS10105 2070605..2070796 - 192 WP_002911395.1 YebW family protein -
KW561_RS10110 2070894..2071133 - 240 WP_002911393.1 YebV family protein -
KW561_RS10115 2071249..2072682 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T209660 NZ_CP079668:2068104-2068206 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT209660 NZ_CP079668:c2068213-2068068 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References